TMEM201 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TMEM201 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMEM201 at tissue level.

III. Associated gene sets

GO_0010761Biological processfibroblast migration
GO_0030473Biological processnuclear migration along microtubule
GO_0031965Cellular componentnuclear membrane
GO_0000922Cellular componentspindle pole
GO_0005637Cellular componentnuclear inner membrane
GO_0005737Cellular componentcytoplasm
GO_0005521Molecular functionlamin binding
GO_0051015Molecular functionactin filament binding

IV. Literature review

[source]
Gene nameTMEM201
Protein nameTransmembrane protein 201 (Spindle-associated membrane protein 1)
Transmembrane protein 201
SynonymsNET5
SAMP1
DescriptionFUNCTION: Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin-dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery . .; FUNCTION: [Isoform 2]: May define a distinct membrane domain in the vicinity of the mitotic spindle . Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina . .

AccessionsH0Y994
ENST00000508400.1
H0Y4R5
ENST00000416541.5
ENST00000340381.11 [Q5SNT2-1]
Q5SNT2
ENST00000340305.9 [Q5SNT2-2]