TMEM119 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMEM119 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	99%	3215.60	454 / 459	95%	53.05	1058 / 1118
lung	100%	4262.71	576 / 578	86%	28.06	994 / 1155
prostate	90%	1553.49	221 / 245	87%	20.65	437 / 502
bladder	100%	2727.33	21 / 21	68%	18.17	344 / 504
skin	91%	4995.18	1646 / 1809	68%	19.99	319 / 472
intestine	76%	1102.60	735 / 966	76%	22.70	402 / 527
stomach	70%	680.31	252 / 359	80%	26.30	229 / 286
thymus	96%	2664.12	626 / 653	47%	10.14	286 / 605
pancreas	48%	408.60	157 / 328	92%	70.02	164 / 178
uterus	85%	1938.79	145 / 170	43%	19.88	199 / 459
brain	28%	236.74	744 / 2642	91%	40.63	641 / 705
esophagus	52%	456.51	750 / 1445	48%	9.00	87 / 183
adrenal gland	51%	358.98	132 / 258	45%	12.18	104 / 230
adipose	95%	2706.41	1146 / 1204	0%	0	0 / 0
spleen	93%	1338.25	225 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	81.65	27 / 29
kidney	45%	570.42	40 / 89	41%	10.56	370 / 901
tonsil	0%	0	0 / 0	73%	14.20	33 / 45
ovary	8%	89.48	15 / 180	54%	14.00	234 / 430
blood vessel	54%	783.05	721 / 1335	0%	0	0 / 0
heart	39%	406.32	332 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	30%	8.60	24 / 80
peripheral blood	26%	408.67	240 / 929	0%	0	0 / 0
liver	0%	2.78	1 / 226	21%	4.26	85 / 406
muscle	5%	34.13	39 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_1903012	Biological process	positive regulation of bone development
GO_0010628	Biological process	positive regulation of gene expression
GO_0010832	Biological process	negative regulation of myotube differentiation
GO_0045779	Biological process	negative regulation of bone resorption
GO_0007283	Biological process	spermatogenesis
GO_0031214	Biological process	biomineral tissue development
GO_0001934	Biological process	positive regulation of protein phosphorylation
GO_0001958	Biological process	endochondral ossification
GO_0030501	Biological process	positive regulation of bone mineralization
GO_0048515	Biological process	spermatid differentiation
GO_0033690	Biological process	positive regulation of osteoblast proliferation
GO_0045669	Biological process	positive regulation of osteoblast differentiation
GO_0001649	Biological process	osteoblast differentiation
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0003674	Molecular function	molecular_function

Gene name	TMEM119
Protein name	Transmembrane protein 119 Transmembrane protein 119 (Osteoblast induction factor) (OBIF)
Synonyms	UNQ731/PRO1415 PSEC0199
Description	FUNCTION: Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts . May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity). .
Accessions	ENST00000549447.1 Q4V9L6 F8VS22 ENST00000392806.4 F8W0W9 ENST00000549031.1 F8VZL0 ENST00000547567.1

TMEM119 report