TMC2 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	3 studies	23% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMC2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	607.21	2593 / 2642	3%	0.07	24 / 705
breast	97%	110.16	446 / 459	1%	0.03	14 / 1118
adipose	97%	111.11	1164 / 1204	0%	0	0 / 0
lung	93%	101.00	535 / 578	3%	0.22	39 / 1155
spleen	87%	39.39	209 / 241	0%	0	0 / 0
bladder	81%	55.52	17 / 21	2%	0.03	11 / 504
adrenal gland	28%	18.07	71 / 258	43%	1.47	99 / 230
ovary	69%	26.48	124 / 180	0%	0.02	2 / 430
uterus	65%	22.58	111 / 170	0%	0.00	2 / 459
intestine	55%	18.50	530 / 966	5%	0.09	28 / 527
esophagus	52%	20.14	757 / 1445	3%	0.09	6 / 183
thymus	49%	14.30	320 / 653	0%	0	0 / 605
blood vessel	49%	20.89	649 / 1335	0%	0	0 / 0
skin	44%	20.64	787 / 1809	1%	0.02	3 / 472
muscle	41%	16.34	330 / 803	0%	0	0 / 0
pancreas	40%	12.34	132 / 328	1%	0.01	1 / 178
prostate	39%	10.35	95 / 245	0%	0.00	1 / 502
stomach	29%	11.83	104 / 359	7%	0.10	19 / 286
heart	13%	3.84	112 / 861	0%	0	0 / 0
kidney	9%	1.80	8 / 89	0%	0.00	1 / 901
peripheral blood	7%	1.54	61 / 929	0%	0	0 / 0
liver	1%	0.19	2 / 226	0%	0.01	1 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0060005	Biological process	vestibular reflex
GO_0050910	Biological process	detection of mechanical stimulus involved in sensory perception of sound
GO_1903169	Biological process	regulation of calcium ion transmembrane transport
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0005575	Cellular component	cellular_component
GO_0032426	Cellular component	stereocilium tip
GO_0005886	Cellular component	plasma membrane
GO_0005245	Molecular function	voltage-gated calcium channel activity
GO_0008381	Molecular function	mechanosensitive monoatomic ion channel activity
GO_0003674	Molecular function	molecular_function

Gene name	TMC2
Protein name	Transmembrane channel-like protein Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2)
Synonyms	UNQ907/PRO1928 C20orf145
Description	FUNCTION: Probable ion channel required for the normal function of cochlear hair cells . Component of the hair cell's mechanotransduction (MET) machinery. Involved in mechanosensitive responses of the hair cells (By similarity). .
Accessions	Q8TDI7 ENST00000358864.2 [Q8TDI7-1] A0A2R8YFP4 ENST00000496948.2

TMC2 report