TKTL2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TKTL2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TKTL2 at tissue level.

III. Associated gene sets

GO_0005737Cellular componentcytoplasm
GO_0046872Molecular functionmetal ion binding
GO_0004802Molecular functiontransketolase activity
GO_0030976Molecular functionthiamine pyrophosphate binding

IV. Literature review

[source]
Gene nameTKTL2
Protein nameTransketolase-like protein 2 (EC 2.2.1.1)
transketolase (EC 2.2.1.1)
SynonymshCG_1645659
DescriptionFUNCTION: Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. .

AccessionsENST00000280605.5
A0A140VKC2
Q9H0I9