Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| microglial cell | 7 studies | 26% ± 8% |
Insufficient scRNA-seq data for expression of SYT6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 89% | 588.15 | 2357 / 2642 | 98% | 14.89 | 690 / 705 |
| pancreas | 99% | 353.10 | 326 / 328 | 11% | 0.38 | 20 / 178 |
| kidney | 88% | 264.36 | 78 / 89 | 20% | 0.45 | 184 / 901 |
| prostate | 55% | 53.56 | 134 / 245 | 42% | 1.50 | 213 / 502 |
| ovary | 70% | 184.93 | 126 / 180 | 2% | 0.08 | 9 / 430 |
| intestine | 50% | 44.96 | 484 / 966 | 1% | 0.03 | 5 / 527 |
| skin | 16% | 8.39 | 285 / 1809 | 33% | 3.35 | 156 / 472 |
| adrenal gland | 22% | 23.36 | 57 / 258 | 22% | 2.97 | 51 / 230 |
| breast | 24% | 11.51 | 108 / 459 | 9% | 0.21 | 106 / 1118 |
| stomach | 28% | 14.50 | 99 / 359 | 0% | 0.00 | 1 / 286 |
| muscle | 23% | 15.78 | 182 / 803 | 0% | 0 | 0 / 0 |
| uterus | 3% | 1.10 | 5 / 170 | 8% | 0.50 | 36 / 459 |
| bladder | 10% | 3.00 | 2 / 21 | 1% | 0.02 | 5 / 504 |
| adipose | 9% | 6.30 | 111 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 4% | 1.89 | 23 / 653 | 2% | 0.04 | 13 / 605 |
| blood vessel | 5% | 3.21 | 72 / 1335 | 0% | 0 | 0 / 0 |
| lung | 3% | 1.17 | 15 / 578 | 3% | 0.16 | 31 / 1155 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.06 | 2 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.29 | 1 / 45 |
| esophagus | 1% | 0.62 | 19 / 1445 | 0% | 0 | 0 / 183 |
| liver | 0% | 0.15 | 1 / 226 | 0% | 0.02 | 1 / 406 |
| heart | 0% | 0.22 | 4 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.22 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0017156 | Biological process | calcium-ion regulated exocytosis |
| GO_0060478 | Biological process | acrosomal vesicle exocytosis |
| GO_0070382 | Cellular component | exocytic vesicle |
| GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0097038 | Cellular component | perinuclear endoplasmic reticulum |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0030276 | Molecular function | clathrin binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0000149 | Molecular function | SNARE binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0001786 | Molecular function | phosphatidylserine binding |
| GO_0005544 | Molecular function | calcium-dependent phospholipid binding |
| GO_0019905 | Molecular function | syntaxin binding |
| Gene name | SYT6 |
| Protein name | Synaptotagmin 6 (Synaptotagmin VI, isoform CRA_b) Synaptotagmin 6 Synaptotagmin-6 (Synaptotagmin VI) (SytVI) Synaptotagmin VI |
| Synonyms | hCG_38646 |
| Description | FUNCTION: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (By similarity). . |
| Accessions | ENST00000641643.2 ENST00000610121.5 Q5T7P8 ENST00000609117.5 [Q5T7P8-2] ENST00000607941.5 [Q5T7P8-2] A0A7I2PMW4 V9GYC4 V9GYB1 A0A286YEX2 ENST00000610222.3 [Q5T7P8-1] ENST00000610096.1 ENST00000609577.1 I6L9C3 ENST00000608879.1 V9GYY7 ENST00000608203.1 V9GY33 ENST00000369547.6 |