SYT5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048791Biological processcalcium ion-regulated exocytosis of neurotransmitter
GO_0048488Biological processsynaptic vesicle endocytosis
GO_0017158Biological processregulation of calcium ion-dependent exocytosis
GO_0007268Biological processchemical synaptic transmission
GO_0070382Cellular componentexocytic vesicle
GO_0005886Cellular componentplasma membrane
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0055038Cellular componentrecycling endosome membrane
GO_1990769Cellular componentproximal neuron projection
GO_0099012Cellular componentneuronal dense core vesicle membrane
GO_0043025Cellular componentneuronal cell body
GO_0031045Cellular componentdense core granule
GO_0030424Cellular componentaxon
GO_0005544Molecular functioncalcium-dependent phospholipid binding
GO_0005546Molecular functionphosphatidylinositol-4,5-bisphosphate binding
GO_0001786Molecular functionphosphatidylserine binding
GO_0000149Molecular functionSNARE binding
GO_0030276Molecular functionclathrin binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0005509Molecular functioncalcium ion binding
GO_0019905Molecular functionsyntaxin binding

IV. Literature review

[source]
Gene nameSYT5
Protein nameSynaptotagmin 5
Synaptotagmin-5 (Synaptotagmin V) (SytV)
SYT5 protein (Synaptotagmin V, isoform CRA_b)
SynonymshCG_19984
DescriptionFUNCTION: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity). .

AccessionsK7EQ59
M0QYJ7
K7EJS7
ENST00000587067.1
K7EJ95
ENST00000354308.8 [O00445-1]
ENST00000590851.5 [O00445-2]
O00445
ENST00000592470.1
ENST00000537500.5 [O00445-1]
ENST00000590859.1
Q05BS5
ENST00000589172.5
ENST00000585461.1
K7EJC4