SUN3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SUN3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SUN3 at tissue level.

III. Associated gene sets

GO_0005637Cellular componentnuclear inner membrane
GO_0005635Cellular componentnuclear envelope
GO_0034993Cellular componentmeiotic nuclear membrane microtubule tethering complex
GO_0043495Molecular functionprotein-membrane adaptor activity

IV. Literature review

[source]
Gene nameSUN3
Protein nameSUN domain-containing protein 3 (Sad1/unc-84 domain-containing protein 1)
Sad1 and UNC84 domain containing 3
SynonymsSUNC1
DescriptionFUNCTION: As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenesis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette. .

AccessionsENST00000412142.5 [Q8TAQ9-3]
H7BZA7
ENST00000395572.6 [Q8TAQ9-1]
ENST00000449896.2
ENST00000438771.5 [Q8TAQ9-2]
ENST00000453071.5
F8WDT4
Q8TAQ9
ENST00000412371.5
ENST00000297325.9 [Q8TAQ9-1]
H7C2N0