SULT1C4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SULT1C4 at tissue level.

III. Associated gene sets

GO_0050427Biological process3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO_0009812Biological processflavonoid metabolic process
GO_0006805Biological processxenobiotic metabolic process
GO_0006068Biological processethanol catabolic process
GO_0051923Biological processsulfation
GO_0044598Biological processdoxorubicin metabolic process
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0008146Molecular functionsulfotransferase activity
GO_0004062Molecular functionaryl sulfotransferase activity

IV. Literature review

[source]
Gene nameSULT1C4
Protein nameSulfotransferase (EC 2.8.2.-)
Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.1) (Sulfotransferase 1C2) (SULT1C#2)
SynonymshCG_27301
SULT1C2
DescriptionFUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. Can also sulfonate estrogenic compounds, however, the dietary flavonoids (phytoestrogen) and environmental estrogens, like bisphenol A are better substrates than 17beta-estradiol (E2) . Mediates the sulfation of doxorubicin and its analog epirubicin, two antitumor anthracyclines . .

AccessionsQ6PD90
ENST00000272452.7 [O75897-1]
ENST00000409309.3 [O75897-2]
O75897