Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 11 studies | 59% ± 24% | |
type I pneumocyte | 8 studies | 51% ± 24% | |
GABAergic neuron | 7 studies | 44% ± 18% | |
neuron | 5 studies | 39% ± 17% | |
interneuron | 5 studies | 39% ± 21% | |
astrocyte | 5 studies | 31% ± 16% | |
endothelial cell | 4 studies | 45% ± 16% | |
retinal bipolar neuron | 4 studies | 40% ± 17% | |
amacrine cell | 4 studies | 60% ± 21% | |
fibroblast | 4 studies | 27% ± 7% | |
GABAergic interneuron | 3 studies | 40% ± 1% | |
GABAergic amacrine cell | 3 studies | 24% ± 7% | |
rod bipolar cell | 3 studies | 71% ± 31% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 12 studies | 40% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 97% | 391.79 | 174 / 180 | 89% | 23.96 | 384 / 430 |
adrenal gland | 100% | 783.57 | 257 / 258 | 66% | 6.13 | 151 / 230 |
lung | 99% | 812.58 | 573 / 578 | 66% | 3.70 | 761 / 1155 |
bladder | 95% | 703.05 | 20 / 21 | 37% | 2.02 | 188 / 504 |
breast | 56% | 284.85 | 256 / 459 | 72% | 10.14 | 808 / 1118 |
stomach | 67% | 429.00 | 239 / 359 | 48% | 3.06 | 136 / 286 |
intestine | 72% | 421.43 | 695 / 966 | 35% | 1.60 | 183 / 527 |
brain | 69% | 926.58 | 1822 / 2642 | 37% | 2.93 | 261 / 705 |
esophagus | 59% | 192.31 | 848 / 1445 | 36% | 1.46 | 66 / 183 |
prostate | 51% | 145.09 | 126 / 245 | 42% | 3.09 | 211 / 502 |
blood vessel | 83% | 594.63 | 1111 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 1% | 2.27 | 3 / 328 | 64% | 5.32 | 114 / 178 |
thymus | 2% | 2.99 | 10 / 653 | 56% | 8.18 | 337 / 605 |
uterus | 18% | 37.46 | 31 / 170 | 26% | 2.46 | 121 / 459 |
skin | 12% | 21.45 | 224 / 1809 | 29% | 2.35 | 137 / 472 |
heart | 25% | 49.53 | 213 / 861 | 0% | 0 | 0 / 0 |
kidney | 2% | 3.75 | 2 / 89 | 18% | 2.14 | 163 / 901 |
adipose | 9% | 21.15 | 112 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 9% | 0.30 | 4 / 45 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
liver | 0% | 0 | 0 / 226 | 3% | 0.16 | 13 / 406 |
spleen | 2% | 7.18 | 6 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.08 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009312 | Biological process | oligosaccharide biosynthetic process |
GO_0001574 | Biological process | ganglioside biosynthetic process |
GO_0006688 | Biological process | glycosphingolipid biosynthetic process |
GO_0009311 | Biological process | oligosaccharide metabolic process |
GO_0006486 | Biological process | protein glycosylation |
GO_0000139 | Cellular component | Golgi membrane |
GO_0001665 | Molecular function | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity |
GO_0008373 | Molecular function | sialyltransferase activity |
Gene name | ST6GALNAC5 |
Protein name | Siat7e Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
Synonyms | SIAT7E |
Description | FUNCTION: Predominantly catalyzes the biosynthesis of ganglioside GD1alpha from GM1b in the brain, by transferring the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of GM1b . GD1alpha is a critical molecule in the communication and interaction between neuronal cells and their supportive cells, particularly in brain tissues, and functions as an adhesion molecule in the process of metastasis (By similarity). Also shows activity towards sialyl Lc4Cer (N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine) generating disialyl Lc4Cer, which can lead to the synthesis of disialyl Lewis a (Le(a)), suggested to be a cancer-associated antigen . . |
Accessions | V5N4G2 ENST00000477717.6 ENST00000318803.6 Q9BVH7 F2Z2C8 |