SPRR2B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SPRR2B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SPRR2B at tissue level.

III. Associated gene sets

GO_0030216Biological processkeratinocyte differentiation
GO_0031424Biological processkeratinization
GO_0008544Biological processepidermis development
GO_0001533Cellular componentcornified envelope
GO_0005829Cellular componentcytosol

IV. Literature review

[source]
Gene nameSPRR2B
Protein nameSmall proline-rich protein 2B (SPR-2B)
Synonyms
DescriptionFUNCTION: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.

AccessionsP35325
ENST00000368755.3