SMOX | OmnibusX

Name	Number of supported studies	Average coverage
platelet	8 studies	29% ± 8%	Explore
astrocyte	7 studies	27% ± 8%	Explore
erythrocyte	4 studies	27% ± 5%	Explore
oligodendrocyte precursor cell	3 studies	18% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SMOX at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3701.13	2642 / 2642	100%	155.64	705 / 705
prostate	99%	1399.69	243 / 245	99%	51.90	497 / 502
skin	99%	1234.99	1798 / 1809	95%	38.79	450 / 472
stomach	98%	1580.03	353 / 359	92%	26.24	263 / 286
pancreas	90%	570.27	296 / 328	94%	39.32	168 / 178
uterus	98%	1104.37	166 / 170	85%	30.33	392 / 459
intestine	80%	485.29	776 / 966	95%	29.01	502 / 527
ovary	100%	1302.97	180 / 180	73%	12.34	315 / 430
thymus	97%	770.16	633 / 653	72%	13.52	437 / 605
esophagus	75%	508.44	1077 / 1445	93%	25.25	171 / 183
kidney	84%	1048.29	75 / 89	82%	19.69	735 / 901
lung	83%	495.03	478 / 578	83%	22.50	956 / 1155
bladder	86%	562.14	18 / 21	77%	19.48	386 / 504
breast	82%	575.19	376 / 459	63%	12.86	707 / 1118
adrenal gland	61%	361.87	157 / 258	56%	10.74	128 / 230
eye	0%	0	0 / 0	100%	31.68	80 / 80
spleen	92%	653.31	221 / 241	0%	0	0 / 0
blood vessel	83%	685.36	1102 / 1335	0%	0	0 / 0
adipose	80%	597.86	966 / 1204	0%	0	0 / 0
peripheral blood	80%	1076.46	740 / 929	0%	0	0 / 0
liver	28%	429.87	64 / 226	50%	13.33	202 / 406
heart	57%	340.59	493 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	53%	12.57	24 / 45
muscle	25%	112.04	197 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	14%	1.91	4 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006598	Biological process	polyamine catabolic process
GO_0046208	Biological process	spermine catabolic process
GO_0006805	Biological process	xenobiotic metabolic process
GO_0006596	Biological process	polyamine biosynthetic process
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0031965	Cellular component	nuclear membrane
GO_0046592	Molecular function	polyamine oxidase activity
GO_0052894	Molecular function	norspermine:oxygen oxidoreductase activity
GO_0052895	Molecular function	N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity
GO_0052901	Molecular function	spermine:oxygen oxidoreductase (spermidine-forming) activity

Gene name	SMOX
Protein name	Spermine oxidase Spermine oxidase (EC 1.5.3.16) (Polyamine oxidase 1) (PAO-1) (PAOh1)
Synonyms	C20orf16 UNQ3039/PRO9854 SMO
Description	FUNCTION: Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Accessions	ENST00000379460.6 [Q9NWM0-1] ENST00000339123.10 [Q9NWM0-2] ENST00000346595.6 [Q9NWM0-3] Q5TE25 ENST00000278795.7 [Q9NWM0-4] ENST00000305958.9 [Q9NWM0-1] ENST00000621355.4 [Q9NWM0-6] Q9NWM0 ENST00000457205.1

SMOX report