SLC9A2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC9A2 at tissue level.

III. Associated gene sets

GO_0098719Biological processsodium ion import across plasma membrane
GO_0006811Biological processmonoatomic ion transport
GO_0008104Biological processprotein localization
GO_0051453Biological processregulation of intracellular pH
GO_0030855Biological processepithelial cell differentiation
GO_1902600Biological processproton transmembrane transport
GO_0071805Biological processpotassium ion transmembrane transport
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0015385Molecular functionsodium:proton antiporter activity
GO_0015386Molecular functionpotassium:proton antiporter activity

IV. Literature review

[source]
Gene nameSLC9A2
Protein nameSodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2)
SynonymsNHE2
DescriptionFUNCTION: Plasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) . Major apical Na(+)/H(+) exchanger in the base of the colonic crypt. Controls in the colonic crypt intracellular pH (pHi) to direct colonic epithelial cell differentiation into the absorptive enterocyte lineage at the expense of the secretory lineage (By similarity). .

AccessionsENST00000233969.3
Q9UBY0