SLC7A13 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SLC7A13 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC7A13 at tissue level.

III. Associated gene sets

GO_0015811Biological processL-cystine transport
GO_0015813Biological processL-glutamate transmembrane transport
GO_0015810Biological processaspartate transmembrane transport
GO_0003333Biological processamino acid transmembrane transport
GO_0016324Cellular componentapical plasma membrane
GO_0046982Molecular functionprotein heterodimerization activity
GO_0015297Molecular functionantiporter activity
GO_0015179Molecular functionL-amino acid transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC7A13
Protein nameSolute carrier family 7 member 13 (Sodium-independent aspartate/glutamate transporter 1) (X-amino acid transporter 2)
SynonymsAGT1
XAT2
DescriptionFUNCTION: Associates with SLC3A1/rBAT to form a functional heterodimeric complex that transports anionic and neutral amino acids across the apical plasma membrane of renal epithelium. Preferentially mediates exchange transport, but can also operate via facilitated diffusion. May act as a major transporter for L-cystine in late proximal tubules, ensuring its reabsorption from the luminal fluid in exchange for cytosolic L-glutamate or L-aspartate. .

AccessionsENST00000419776.2 [Q8TCU3-2]
ENST00000297524.8 [Q8TCU3-1]
Q8TCU3