Insufficient scRNA-seq data for expression of SLC66A1 at single-cell level.
Insufficient scRNA-seq data for expression of SLC66A1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 761.40 | 1445 / 1445 | 100% | 20.07 | 183 / 183 |
liver | 100% | 1269.13 | 226 / 226 | 100% | 24.09 | 406 / 406 |
ovary | 100% | 843.32 | 180 / 180 | 100% | 22.57 | 430 / 430 |
pancreas | 100% | 844.70 | 328 / 328 | 100% | 21.63 | 178 / 178 |
skin | 100% | 1176.48 | 1809 / 1809 | 100% | 41.15 | 472 / 472 |
thymus | 100% | 1212.00 | 653 / 653 | 100% | 27.66 | 605 / 605 |
uterus | 100% | 1032.59 | 170 / 170 | 100% | 28.76 | 459 / 459 |
brain | 100% | 1115.16 | 2639 / 2642 | 100% | 26.20 | 705 / 705 |
adrenal gland | 100% | 2081.23 | 258 / 258 | 100% | 26.84 | 229 / 230 |
kidney | 100% | 1127.11 | 89 / 89 | 99% | 19.06 | 896 / 901 |
intestine | 100% | 1056.46 | 966 / 966 | 99% | 18.08 | 524 / 527 |
prostate | 100% | 1274.49 | 245 / 245 | 99% | 23.12 | 499 / 502 |
breast | 100% | 961.14 | 459 / 459 | 99% | 22.86 | 1111 / 1118 |
stomach | 100% | 971.06 | 359 / 359 | 99% | 18.62 | 284 / 286 |
lung | 100% | 979.69 | 576 / 578 | 100% | 23.33 | 1150 / 1155 |
bladder | 100% | 850.29 | 21 / 21 | 99% | 25.68 | 497 / 504 |
adipose | 100% | 895.74 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 33.12 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 23.98 | 29 / 29 |
spleen | 100% | 1198.27 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 23.08 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 29.70 | 1 / 1 |
blood vessel | 100% | 622.14 | 1329 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 718.05 | 797 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 543.30 | 848 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 93% | 519.17 | 865 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0089709 | Biological process | L-histidine transmembrane transport |
GO_1903826 | Biological process | L-arginine transmembrane transport |
GO_1903401 | Biological process | L-lysine transmembrane transport |
GO_0080144 | Biological process | intracellular amino acid homeostasis |
GO_0015819 | Biological process | lysine transport |
GO_0055085 | Biological process | transmembrane transport |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0031090 | Cellular component | organelle membrane |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0061459 | Molecular function | L-arginine transmembrane transporter activity |
GO_0015189 | Molecular function | L-lysine transmembrane transporter activity |
GO_0005290 | Molecular function | L-histidine transmembrane transporter activity |
GO_0015174 | Molecular function | basic amino acid transmembrane transporter activity |
Gene name | SLC66A1 |
Protein name | PQ loop repeat containing 2 isoform 1 (PQ loop repeat containing 2, isoform CRA_b) Lysosomal amino acid transporter 1 homolog (PQ-loop repeat-containing protein 2) (Solute carrier family 66 member 1) PQ loop repeat containing 2 isoform 2 (Solute carrier family 66 member 1) Solute carrier family 66 member 1 |
Synonyms | hCG_41084 PQLC2 |
Description | FUNCTION: Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes. . |
Accessions | E9PL93 ENST00000497827.1 ENST00000375155.7 [Q6ZP29-1] ENST00000469076.5 ENST00000432465.1 A0A024RAA1 E9PJZ6 ENST00000375153.8 [Q6ZP29-1] Q6ZP29 A2A2E6 ENST00000400548.6 [Q6ZP29-3] |