SLC5A12 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell of proximal tubule	8 studies	40% ± 22%	Explore
enterocyte	6 studies	28% ± 9%	Explore

Name	Number of supported studies	Average coverage
kidney	4 studies	23% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	14793.27	89 / 89	60%	28.50	542 / 901
brain	88%	94.71	2333 / 2642	10%	0.14	72 / 705
intestine	85%	1115.49	824 / 966	8%	0.22	40 / 527
spleen	90%	71.05	218 / 241	0%	0	0 / 0
esophagus	29%	6.35	424 / 1445	58%	1.99	107 / 183
bladder	62%	29.81	13 / 21	26%	0.63	129 / 504
liver	66%	90.43	150 / 226	11%	0.55	46 / 406
lung	27%	5.30	155 / 578	32%	0.97	373 / 1155
adipose	56%	15.41	672 / 1204	0%	0	0 / 0
heart	54%	513.40	467 / 861	0%	0	0 / 0
ovary	25%	4.38	45 / 180	23%	0.69	99 / 430
breast	40%	7.88	182 / 459	6%	0.22	70 / 1118
uterus	34%	7.17	57 / 170	12%	0.31	54 / 459
blood vessel	45%	13.76	598 / 1335	0%	0	0 / 0
adrenal gland	43%	8.06	111 / 258	0%	0.01	1 / 230
thymus	29%	5.66	187 / 653	8%	0.39	49 / 605
skin	26%	4.87	465 / 1809	11%	0.62	52 / 472
prostate	35%	7.60	85 / 245	1%	0.01	3 / 502
stomach	22%	5.94	80 / 359	12%	0.31	35 / 286
pancreas	2%	0.16	5 / 328	9%	0.27	16 / 178
muscle	8%	1.50	68 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	7%	0.11	3 / 45
lymph node	0%	0	0 / 0	3%	0.11	1 / 29
peripheral blood	1%	0.12	8 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006811	Biological process	monoatomic ion transport
GO_0015718	Biological process	monocarboxylic acid transport
GO_0006814	Biological process	sodium ion transport
GO_0035873	Biological process	lactate transmembrane transport
GO_0016324	Cellular component	apical plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005886	Cellular component	plasma membrane
GO_0005343	Molecular function	organic acid:sodium symporter activity
GO_0015293	Molecular function	symporter activity
GO_0015129	Molecular function	lactate transmembrane transporter activity
GO_0140161	Molecular function	monocarboxylate:sodium symporter activity

Gene name	SLC5A12
Protein name	Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12) SLC5A12 protein (Solute carrier family 5 (Sodium/glucose cotransporter), member 12, isoform CRA_c) Solute carrier family 5 (Sodium/glucose cotransporter), member 12, isoform CRA_b (Solute carrier family 5 member 12) Solute carrier family 5 member 12
Synonyms	hCG_2036627 SMCT2
Description	FUNCTION: Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter . Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate (By similarity). May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). .
Accessions	E9PLZ7 G3V1E3 Q1EHB4 ENST00000396005.8 [Q1EHB4-1] ENST00000280467.10 [Q1EHB4-2] ENST00000527405.5 Q8IUS7 ENST00000533617.5

SLC5A12 report