SLC5A10 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC5A10 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	1812.70	89 / 89	77%	13.79	692 / 901
skin	74%	49.93	1332 / 1809	28%	0.79	130 / 472
spleen	100%	277.33	241 / 241	0%	0	0 / 0
lung	97%	41.78	563 / 578	1%	0.01	6 / 1155
liver	90%	21.71	203 / 226	8%	0.23	32 / 406
peripheral blood	97%	71.28	899 / 929	0%	0	0 / 0
thymus	95%	31.54	623 / 653	0%	0.00	2 / 605
breast	91%	20.41	418 / 459	1%	0.02	11 / 1118
adrenal gland	88%	18.31	228 / 258	0%	0.00	1 / 230
eye	0%	0	0 / 0	89%	3.71	71 / 80
adipose	86%	21.21	1033 / 1204	0%	0	0 / 0
uterus	84%	21.22	143 / 170	1%	0.02	5 / 459
prostate	84%	19.74	206 / 245	0%	0.01	1 / 502
heart	84%	38.24	721 / 861	0%	0	0 / 0
ovary	76%	15.92	137 / 180	0%	0	0 / 430
esophagus	65%	19.42	933 / 1445	2%	0.03	4 / 183
intestine	66%	34.80	634 / 966	1%	0.01	3 / 527
bladder	57%	13.90	12 / 21	0%	0	0 / 504
stomach	35%	4.87	126 / 359	0%	0	0 / 286
brain	32%	4.26	856 / 2642	0%	0	0 / 705
blood vessel	29%	5.04	382 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	14%	0.17	4 / 29
muscle	10%	1.07	82 / 803	0%	0	0 / 0
pancreas	6%	0.79	21 / 328	1%	0.01	2 / 178
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0015761	Biological process	mannose transmembrane transport
GO_0008645	Biological process	hexose transmembrane transport
GO_1904659	Biological process	glucose transmembrane transport
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0015755	Biological process	fructose transmembrane transport
GO_0016324	Cellular component	apical plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005886	Cellular component	plasma membrane
GO_0140930	Molecular function	fructose:sodium symporter activity
GO_0005412	Molecular function	glucose:sodium symporter activity
GO_0140929	Molecular function	mannose:sodium symporter activity
GO_0015370	Molecular function	solute:sodium symporter activity

Gene name	SLC5A10
Protein name	Sodium/mannose cotransporter SLC5A10 (Sodium/glucose cotransporter 5) (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10)
Synonyms	SGLT5
Description	FUNCTION: [Isoform 1]: Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2 . Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney . .; FUNCTION: [Isoform 2]: Appears to have no transporter activity. .
Accessions	ENST00000395643.6 [A0PJK1-2] ENST00000395647.6 [A0PJK1-4] ENST00000395645.4 [A0PJK1-1] A0PJK1 ENST00000317977.10 [A0PJK1-3] ENST00000417251.6 [A0PJK1-5]

SLC5A10 report