SLC4A9 | OmnibusX

Name	Number of supported studies	Average coverage
renal beta-intercalated cell	4 studies	94% ± 4%	Explore
renal alpha-intercalated cell	3 studies	41% ± 12%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC4A9 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	5186.69	89 / 89	10%	1.90	92 / 901
thymus	99%	45.30	644 / 653	1%	0.04	5 / 605
brain	98%	44.23	2588 / 2642	1%	0.03	9 / 705
lung	92%	21.71	532 / 578	2%	0.04	24 / 1155
adipose	82%	20.09	992 / 1204	0%	0	0 / 0
prostate	80%	24.23	197 / 245	1%	0.01	4 / 502
pancreas	74%	14.56	242 / 328	1%	0.02	2 / 178
esophagus	67%	11.50	974 / 1445	7%	0.16	12 / 183
heart	69%	11.01	593 / 861	0%	0	0 / 0
spleen	68%	10.06	165 / 241	0%	0	0 / 0
stomach	62%	7.04	224 / 359	4%	0.07	11 / 286
peripheral blood	65%	19.62	602 / 929	0%	0	0 / 0
breast	61%	7.92	280 / 459	0%	0.01	5 / 1118
bladder	57%	9.33	12 / 21	4%	0.07	19 / 504
intestine	55%	6.65	528 / 966	1%	0.02	5 / 527
uterus	49%	5.91	84 / 170	1%	0.02	5 / 459
skin	48%	6.51	870 / 1809	0%	0	0 / 472
blood vessel	48%	6.07	642 / 1335	0%	0	0 / 0
adrenal gland	47%	5.50	120 / 258	0%	0.01	1 / 230
muscle	46%	6.56	366 / 803	0%	0	0 / 0
ovary	20%	2.19	36 / 180	2%	0.03	8 / 430
liver	12%	0.96	26 / 226	0%	0.00	1 / 406
lymph node	0%	0	0 / 0	7%	0.17	2 / 29
tonsil	0%	0	0 / 0	2%	0.05	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0046541	Biological process	saliva secretion
GO_0051453	Biological process	regulation of intracellular pH
GO_0015701	Biological process	bicarbonate transport
GO_1902476	Biological process	chloride transmembrane transport
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0055085	Biological process	transmembrane transport
GO_0045177	Cellular component	apical part of cell
GO_0005886	Cellular component	plasma membrane
GO_0016323	Cellular component	basolateral plasma membrane
GO_0140900	Molecular function	chloride:bicarbonate antiporter activity
GO_0140892	Molecular function	sodium,bicarbonate:chloride antiporter activity
GO_0008510	Molecular function	sodium:bicarbonate symporter activity

Gene name	SLC4A9
Protein name	Anion exchange protein 4 (AE 4) (Anion exchanger 4) (Sodium bicarbonate cotransporter 5) (Solute carrier family 4 member 9)
Synonyms	AE4 SBC5
Description	FUNCTION: Electroneutral Cl(-)/HCO3(-) antiporter that favors chloride ion entry and efflux of hydrogencarbonate and sodium ion across the basolateral membrane and may participate in salivary secretion . Also mediates Cl(-)/HCO3(-) exchange activity in the presence of K(+) as well as Cs(+), Li(+), and Rb(+) (By similarity). Does not contribute to Cl(-)/HCO3(-) exchanger in the apical membrane of the upper villous epithelium (By similarity). .
Accessions	ENST00000506757.7 [Q96Q91-3] ENST00000432095.6 [Q96Q91-2] ENST00000507527.1 [Q96Q91-1] ENST00000506545.5 [Q96Q91-4] Q96Q91

SLC4A9 report