SLC45A2 | OmnibusX

Name	Number of supported studies	Average coverage
retinal pigment epithelial cell	3 studies	26% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC45A2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	75%	36.38	1360 / 1809	90%	154.99	427 / 472
prostate	75%	15.42	184 / 245	69%	9.02	344 / 502
liver	96%	67.91	217 / 226	22%	0.82	89 / 406
kidney	94%	45.25	84 / 89	20%	0.77	183 / 901
eye	0%	0	0 / 0	100%	83.00	80 / 80
brain	92%	20.86	2427 / 2642	3%	0.05	21 / 705
stomach	67%	21.85	241 / 359	3%	0.13	10 / 286
adrenal gland	55%	10.59	142 / 258	14%	0.26	32 / 230
muscle	66%	9.68	529 / 803	0%	0	0 / 0
heart	61%	14.26	523 / 861	0%	0	0 / 0
lung	52%	5.41	298 / 578	4%	0.08	42 / 1155
intestine	48%	10.88	465 / 966	3%	0.06	18 / 527
pancreas	42%	3.98	138 / 328	4%	0.14	7 / 178
breast	43%	7.26	196 / 459	2%	0.05	20 / 1118
bladder	38%	2.95	8 / 21	6%	0.14	30 / 504
thymus	37%	3.04	239 / 653	4%	0.12	24 / 605
spleen	40%	4.10	96 / 241	0%	0	0 / 0
uterus	30%	3.41	51 / 170	3%	0.38	14 / 459
ovary	28%	2.36	51 / 180	0%	0.00	1 / 430
peripheral blood	26%	4.20	237 / 929	0%	0	0 / 0
adipose	23%	2.21	280 / 1204	0%	0	0 / 0
blood vessel	22%	1.86	294 / 1335	0%	0	0 / 0
esophagus	18%	1.43	265 / 1445	3%	0.09	6 / 183
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007601	Biological process	visual perception
GO_0048066	Biological process	developmental pigmentation
GO_0015770	Biological process	sucrose transport
GO_1904659	Biological process	glucose transmembrane transport
GO_0006583	Biological process	melanin biosynthetic process from tyrosine
GO_0035752	Biological process	lysosomal lumen pH elevation
GO_0033162	Cellular component	melanosome membrane
GO_0016020	Cellular component	membrane
GO_0008506	Molecular function	sucrose:proton symporter activity
GO_0005356	Molecular function	glucose:proton symporter activity

Gene name	SLC45A2
Protein name	Solute carrier family 45 member 2 Membrane-associated transporter protein SLC45A2 Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Solute carrier family 45 member 2) SLC45A2 (Solute carrier family 45, member 2, isoform CRA_a)
Synonyms	AIM1 MATP hCG_37411
Description	FUNCTION: Proton-associated glucose and sucrose transporter (By similarity). May be able to transport also fructose (By similarity). Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis . Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR . .
Accessions	Q9UMX9 ENST00000631273.1 D6RGY6 D6RBP8 ENST00000626332.2 ENST00000296589.9 [Q9UMX9-1] ENST00000510600.1 A0A0G2JQI6 ENST00000631255.2 A0A0G2JSD6 A0A076YGN1 A0A0G2JQN1 ENST00000509381.1 A0A0G2JSC7 A0A076YN63 ENST00000626082.1 A0A076YIB8 ENST00000382102.7 [Q9UMX9-4]

SLC45A2 report