SLC2A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1904659Biological processglucose transmembrane transport
GO_0015757Biological processgalactose transmembrane transport
GO_0005975Biological processcarbohydrate metabolic process
GO_0015755Biological processfructose transmembrane transport
GO_0070837Biological processdehydroascorbic acid transport
GO_0035774Biological processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
GO_0046323Biological processglucose import
GO_0005903Cellular componentbrush border
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005911Cellular componentcell-cell junction
GO_0005737Cellular componentcytoplasm
GO_0015149Molecular functionhexose transmembrane transporter activity
GO_0005354Molecular functiongalactose transmembrane transporter activity
GO_0055056Molecular functionD-glucose transmembrane transporter activity
GO_0033300Molecular functiondehydroascorbic acid transmembrane transporter activity
GO_0005353Molecular functionfructose transmembrane transporter activity
GO_0005355Molecular functionglucose transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC2A2
Protein nameSLC2A2 protein (Solute carrier family 2 (Facilitated glucose transporter), member 2, isoform CRA_c) (cDNA FLJ75366, highly similar to Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2, mRNA)
Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2)
Alternative protein SLC2A2
Solute carrier family 2 member 2
SynonymsGLUT2
hCG_14921
DescriptionFUNCTION: Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose . Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell . May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney . Also able to mediate the transport of dehydroascorbate . .

AccessionsP11168
F8WBJ2
ENST00000314251.8 [P11168-1]
ENST00000469787.1
C9J0E8
ENST00000497642.5
L8E6W0
A0A0C4DH64
Q6PAU8
ENST00000461867.1