Insufficient scRNA-seq data for expression of SLC29A2 at single-cell level.
Insufficient scRNA-seq data for expression of SLC29A2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 99% | 1366.47 | 243 / 245 | 99% | 22.72 | 498 / 502 |
pancreas | 100% | 898.61 | 328 / 328 | 98% | 23.67 | 174 / 178 |
thymus | 100% | 1217.03 | 653 / 653 | 98% | 14.44 | 590 / 605 |
breast | 94% | 1569.25 | 433 / 459 | 94% | 22.62 | 1056 / 1118 |
brain | 90% | 970.35 | 2366 / 2642 | 95% | 17.56 | 671 / 705 |
lung | 86% | 783.73 | 499 / 578 | 97% | 27.92 | 1121 / 1155 |
stomach | 79% | 922.02 | 285 / 359 | 98% | 39.61 | 281 / 286 |
esophagus | 80% | 420.22 | 1162 / 1445 | 93% | 30.92 | 171 / 183 |
intestine | 61% | 825.10 | 587 / 966 | 99% | 41.10 | 523 / 527 |
liver | 65% | 243.45 | 148 / 226 | 89% | 17.30 | 362 / 406 |
kidney | 100% | 1197.03 | 89 / 89 | 46% | 7.89 | 415 / 901 |
uterus | 52% | 219.36 | 89 / 170 | 92% | 21.85 | 424 / 459 |
bladder | 38% | 207.57 | 8 / 21 | 89% | 23.38 | 449 / 504 |
ovary | 19% | 66.30 | 34 / 180 | 100% | 47.08 | 428 / 430 |
skin | 56% | 273.32 | 1019 / 1809 | 47% | 5.11 | 222 / 472 |
muscle | 100% | 7797.49 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.03 | 1 / 1 |
spleen | 98% | 589.83 | 237 / 241 | 0% | 0 | 0 / 0 |
heart | 94% | 1764.69 | 812 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 17.22 | 40 / 45 |
adipose | 86% | 1065.62 | 1039 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 18% | 64.19 | 46 / 258 | 65% | 6.33 | 150 / 230 |
eye | 0% | 0 | 0 / 0 | 53% | 4.72 | 42 / 80 |
lymph node | 0% | 0 | 0 / 0 | 52% | 4.65 | 15 / 29 |
blood vessel | 43% | 173.84 | 575 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 33% | 254.57 | 304 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0035340 | Biological process | inosine transport |
GO_0006855 | Biological process | xenobiotic transmembrane transport |
GO_0035344 | Biological process | hypoxanthine transport |
GO_1904823 | Biological process | purine nucleobase transmembrane transport |
GO_0035364 | Biological process | thymine transport |
GO_0150104 | Biological process | transport across blood-brain barrier |
GO_0015861 | Biological process | cytidine transport |
GO_0015851 | Biological process | nucleobase transport |
GO_0072531 | Biological process | pyrimidine-containing compound transmembrane transport |
GO_0015858 | Biological process | nucleoside transport |
GO_0001504 | Biological process | neurotransmitter uptake |
GO_0015853 | Biological process | adenine transport |
GO_1903716 | Biological process | guanine transmembrane transport |
GO_0015862 | Biological process | uridine transmembrane transport |
GO_0006836 | Biological process | neurotransmitter transport |
GO_0015860 | Biological process | purine nucleoside transmembrane transport |
GO_0032238 | Biological process | adenosine transport |
GO_0015854 | Biological process | guanine transport |
GO_1903791 | Biological process | uracil transmembrane transport |
GO_1901642 | Biological process | nucleoside transmembrane transport |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005730 | Cellular component | nucleolus |
GO_0005886 | Cellular component | plasma membrane |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0015205 | Molecular function | nucleobase transmembrane transporter activity |
GO_0015211 | Molecular function | purine nucleoside transmembrane transporter activity |
GO_0005326 | Molecular function | neurotransmitter transmembrane transporter activity |
GO_0015207 | Molecular function | adenine transmembrane transporter activity |
GO_0015210 | Molecular function | uracil transmembrane transporter activity |
GO_0015213 | Molecular function | uridine transmembrane transporter activity |
GO_0015208 | Molecular function | guanine transmembrane transporter activity |
GO_0005337 | Molecular function | nucleoside transmembrane transporter activity |
GO_0015212 | Molecular function | cytidine transmembrane transporter activity |
Gene name | SLC29A2 |
Protein name | Equilibrative nucleoside transporter 2 (hENT2) (36 kDa nucleolar protein HNP36) (Delayed-early response protein 12) (Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter) (Equilibrative NBMPR-insensitive nucleoside transporter) (Hydrophobic nucleolar protein, 36 kDa) (Nucleoside transporter, ei-type) (Solute carrier family 29 member 2) |
Synonyms | DER12 HNP36 ENT2 |
Description | FUNCTION: Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis . Functions as a Na(+)-independent, passive transporter . Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine . Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil) . Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites . Mediates apical nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier . Mediates both the influx and efflux of hypoxanthine in skeletal muscle microvascular endothelial cells to control the amount of intracellular hypoxanthine available for xanthine oxidase-mediated ROS production (By similarity). .; FUNCTION: [Isoform 3]: Non functional nucleoside transporter protein for adenosine or thymidine transport. Does not express on cell membrane. . |
Accessions | ENST00000544554.5 [Q14542-1] ENST00000546034.1 [Q14542-1] ENST00000311161.11 [Q14542-4] ENST00000619145.4 [Q14542-4] ENST00000541567.5 [Q14542-2] Q14542 ENST00000540386.5 [Q14542-3] ENST00000357440.7 [Q14542-1] |