Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 26% ± 9% | |
| erythrocyte | 5 studies | 30% ± 16% | |
| fibroblast | 4 studies | 24% ± 8% | |
| adipocyte | 4 studies | 24% ± 5% | |
| erythroblast | 4 studies | 38% ± 14% | |
| pancreatic A cell | 3 studies | 36% ± 14% | |
| GABAergic neuron | 3 studies | 31% ± 5% | |
| glutamatergic neuron | 3 studies | 33% ± 6% | |
| vein endothelial cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreas | 3 studies | 30% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 4925.66 | 328 / 328 | 99% | 78.73 | 177 / 178 |
| breast | 100% | 12020.57 | 459 / 459 | 99% | 116.43 | 1107 / 1118 |
| stomach | 100% | 9364.63 | 359 / 359 | 98% | 74.43 | 280 / 286 |
| thymus | 100% | 7130.32 | 652 / 653 | 97% | 55.95 | 586 / 605 |
| adrenal gland | 100% | 12081.10 | 258 / 258 | 97% | 137.71 | 222 / 230 |
| lung | 99% | 5416.29 | 573 / 578 | 97% | 57.74 | 1123 / 1155 |
| bladder | 100% | 6698.67 | 21 / 21 | 96% | 68.07 | 485 / 504 |
| uterus | 100% | 6703.23 | 170 / 170 | 93% | 60.72 | 428 / 459 |
| skin | 94% | 5834.27 | 1702 / 1809 | 99% | 128.68 | 467 / 472 |
| kidney | 98% | 4170.28 | 87 / 89 | 92% | 49.81 | 825 / 901 |
| intestine | 89% | 9370.81 | 860 / 966 | 99% | 74.68 | 520 / 527 |
| esophagus | 91% | 10239.52 | 1309 / 1445 | 94% | 52.73 | 172 / 183 |
| liver | 83% | 3096.73 | 187 / 226 | 96% | 89.62 | 391 / 406 |
| ovary | 75% | 2275.94 | 135 / 180 | 95% | 48.93 | 410 / 430 |
| prostate | 90% | 3051.93 | 220 / 245 | 77% | 21.45 | 388 / 502 |
| brain | 51% | 1408.59 | 1338 / 2642 | 88% | 40.61 | 621 / 705 |
| adipose | 100% | 12363.43 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 31.12 | 1 / 1 |
| blood vessel | 100% | 11830.37 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 9049.85 | 850 / 861 | 0% | 0 | 0 / 0 |
| muscle | 99% | 6127.10 | 791 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 37.78 | 44 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 66.18 | 28 / 29 |
| spleen | 94% | 2577.46 | 227 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 76% | 26.57 | 61 / 80 |
| peripheral blood | 34% | 1471.60 | 312 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006139 | Biological process | nucleobase-containing compound metabolic process |
| GO_0035340 | Biological process | inosine transport |
| GO_1904082 | Biological process | pyrimidine nucleobase transmembrane transport |
| GO_0071333 | Biological process | cellular response to glucose stimulus |
| GO_0006805 | Biological process | xenobiotic metabolic process |
| GO_0006855 | Biological process | xenobiotic transmembrane transport |
| GO_0035344 | Biological process | hypoxanthine transport |
| GO_1904823 | Biological process | purine nucleobase transmembrane transport |
| GO_0035364 | Biological process | thymine transport |
| GO_0060079 | Biological process | excitatory postsynaptic potential |
| GO_0015861 | Biological process | cytidine transport |
| GO_0150104 | Biological process | transport across blood-brain barrier |
| GO_0015851 | Biological process | nucleobase transport |
| GO_0072531 | Biological process | pyrimidine-containing compound transmembrane transport |
| GO_0015858 | Biological process | nucleoside transport |
| GO_0001504 | Biological process | neurotransmitter uptake |
| GO_0015853 | Biological process | adenine transport |
| GO_1903716 | Biological process | guanine transmembrane transport |
| GO_0015862 | Biological process | uridine transmembrane transport |
| GO_0006836 | Biological process | neurotransmitter transport |
| GO_0015860 | Biological process | purine nucleoside transmembrane transport |
| GO_0032238 | Biological process | adenosine transport |
| GO_0007595 | Biological process | lactation |
| GO_1903791 | Biological process | uracil transmembrane transport |
| GO_1901642 | Biological process | nucleoside transmembrane transport |
| GO_0071456 | Biological process | cellular response to hypoxia |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0098793 | Cellular component | presynapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0098794 | Cellular component | postsynapse |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0015211 | Molecular function | purine nucleoside transmembrane transporter activity |
| GO_0005326 | Molecular function | neurotransmitter transmembrane transporter activity |
| GO_0015207 | Molecular function | adenine transmembrane transporter activity |
| GO_0015389 | Molecular function | pyrimidine- and adenosine-specific:sodium symporter activity |
| GO_0015210 | Molecular function | uracil transmembrane transporter activity |
| GO_0015213 | Molecular function | uridine transmembrane transporter activity |
| GO_0015208 | Molecular function | guanine transmembrane transporter activity |
| GO_0005337 | Molecular function | nucleoside transmembrane transporter activity |
| GO_0015212 | Molecular function | cytidine transmembrane transporter activity |
| Gene name | SLC29A1 |
| Protein name | Equilibrative nucleoside transporter 1 variant ata Solute carrier family 29 member 1 (Augustine blood group) Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 1 (hENT1) (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (es nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1) |
| Synonyms | ENT1 |
| Description | FUNCTION: Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis . Functions as a Na(+)-independent transporter . Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine . Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil) . Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier (By similarity). Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure . . |
| Accessions | ENST00000646251.1 C8KHU2 ENST00000393841.6 ENST00000371713.6 [Q99808-1] ENST00000646582.1 Q99808 A0A2R8Y854 ENST00000643869.1 ENST00000371731.6 ENST00000651428.1 [Q99808-1] ENST00000652453.1 [Q99808-1] ENST00000643028.2 A0A2R8Y801 A0A2U3TZM5 ENST00000371740.10 ENST00000393844.7 [Q99808-1] ENST00000371724.6 [Q99808-1] ENST00000642777.1 ENST00000371755.9 [Q99808-1] A0A2U3TZJ7 ENST00000645692.1 ENST00000371708.1 [Q99808-1] A0A2R8YEH8 A0A2R8YFI6 A0A220K8H0 A0A2U3TZM6 A0A2R8YFB9 C8KHU1 A0A2R8Y567 A0A2R8Y6D1 ENST00000652680.1 [Q99808-1] ENST00000647460.1 A0A0S2C6M1 |
