SLC28A2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SLC28A2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC28A2 at tissue level.

III. Associated gene sets

GO_0006139Biological processnucleobase-containing compound metabolic process
GO_0035340Biological processinosine transport
GO_0001895Biological processretina homeostasis
GO_0006805Biological processxenobiotic metabolic process
GO_0006855Biological processxenobiotic transmembrane transport
GO_1904823Biological processpurine nucleobase transmembrane transport
GO_0150104Biological processtransport across blood-brain barrier
GO_0015855Biological processpyrimidine nucleobase transport
GO_0072531Biological processpyrimidine-containing compound transmembrane transport
GO_0045117Biological processazole transmembrane transport
GO_0015862Biological processuridine transmembrane transport
GO_0006836Biological processneurotransmitter transport
GO_0032238Biological processadenosine transport
GO_0015860Biological processpurine nucleoside transmembrane transport
GO_1901642Biological processnucleoside transmembrane transport
GO_0031526Cellular componentbrush border membrane
GO_0005886Cellular componentplasma membrane
GO_0012506Cellular componentvesicle membrane
GO_0016020Cellular componentmembrane
GO_0030135Cellular componentcoated vesicle
GO_0016327Cellular componentapicolateral plasma membrane
GO_0005415Molecular functionnucleoside:sodium symporter activity
GO_0005345Molecular functionpurine nucleobase transmembrane transporter activity
GO_0015211Molecular functionpurine nucleoside transmembrane transporter activity
GO_0005326Molecular functionneurotransmitter transmembrane transporter activity
GO_1901474Molecular functionazole transmembrane transporter activity
GO_0015389Molecular functionpyrimidine- and adenosine-specific:sodium symporter activity
GO_0015213Molecular functionuridine transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC28A2
Protein nameSodium/nucleoside cotransporter
Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (hCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside co-transporter) (SPNT) (Solute carrier family 28 member 2)
Solute carrier family 28 member 2
SynonymshCG_39000
CNT2
DescriptionFUNCTION: Sodium-dependent and purine-selective transporter . Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine) . Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues . May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). .

AccessionsENST00000560438.5
H0YNK4
H0YNM6
O43868
Q2M2A7
ENST00000347644.8
ENST00000559924.1