SLC28A1 | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	3 studies	61% ± 14%	Explore
epithelial cell of proximal tubule	3 studies	39% ± 11%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC28A1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	3687.75	89 / 89	88%	103.10	789 / 901
liver	100%	6278.00	226 / 226	77%	28.70	314 / 406
muscle	98%	67.01	784 / 803	0%	0	0 / 0
heart	97%	50.11	832 / 861	0%	0	0 / 0
blood vessel	92%	39.84	1234 / 1335	0%	0	0 / 0
breast	78%	19.92	358 / 459	3%	0.25	37 / 1118
uterus	73%	18.15	124 / 170	1%	0.05	4 / 459
adipose	72%	13.09	866 / 1204	0%	0	0 / 0
intestine	54%	225.53	523 / 966	1%	0.09	4 / 527
prostate	52%	6.38	127 / 245	0%	0.01	1 / 502
adrenal gland	52%	6.38	134 / 258	0%	0	0 / 230
bladder	43%	3.76	9 / 21	1%	0.03	4 / 504
spleen	44%	11.76	105 / 241	0%	0	0 / 0
pancreas	42%	4.85	137 / 328	1%	0.06	1 / 178
ovary	38%	4.01	69 / 180	3%	0.13	12 / 430
thymus	39%	3.83	254 / 653	0%	0.01	1 / 605
esophagus	35%	3.98	500 / 1445	1%	0.04	2 / 183
brain	31%	3.86	829 / 2642	3%	0.23	20 / 705
lung	30%	2.99	172 / 578	1%	0.03	7 / 1155
stomach	26%	3.18	93 / 359	0%	0	0 / 286
peripheral blood	25%	3.72	234 / 929	0%	0	0 / 0
skin	18%	1.87	317 / 1809	1%	0.05	3 / 472
eye	0%	0	0 / 0	5%	0.25	4 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_1904823	Biological process	purine nucleobase transmembrane transport
GO_0015861	Biological process	cytidine transport
GO_0015855	Biological process	pyrimidine nucleobase transport
GO_0072531	Biological process	pyrimidine-containing compound transmembrane transport
GO_0045117	Biological process	azole transmembrane transport
GO_0015862	Biological process	uridine transmembrane transport
GO_0180015	Biological process	nucleoside import across plasma membrane
GO_1901642	Biological process	nucleoside transmembrane transport
GO_0031526	Cellular component	brush border membrane
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0016607	Cellular component	nuclear speck
GO_0005829	Cellular component	cytosol
GO_0005415	Molecular function	nucleoside:sodium symporter activity
GO_0005345	Molecular function	purine nucleobase transmembrane transporter activity
GO_1901474	Molecular function	azole transmembrane transporter activity
GO_0015389	Molecular function	pyrimidine- and adenosine-specific:sodium symporter activity
GO_0015213	Molecular function	uridine transmembrane transporter activity
GO_0015212	Molecular function	cytidine transmembrane transporter activity

Gene name	SLC28A1
Protein name	Solute carrier family 28 member 1 (cDNA FLJ58165, highly similar to Sodium/nucleoside cotransporter 1) Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (hCNT1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1)
Synonyms	CNT1
Description	FUNCTION: Sodium and pyrimidine nucleoside symporter of the plasma membrane that imports uridine, thymidine and cytidine into cells by coupling their transport to the transmembrane sodium electrochemical gradient. Also transports adenosine, an atypical substrate transported with high apparent affinity, but low maximum velocity. Therefore, exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) . Involved in renal nucleoside (re)absorption . .
Accessions	O00337 ENST00000286749.3 [O00337-1] B7Z3L6 ENST00000538177.5 ENST00000338602.6 [O00337-2] ENST00000394573.6 [O00337-1]

SLC28A1 report