SLC26A7 | OmnibusX

Name	Number of supported studies	Average coverage
renal alpha-intercalated cell	7 studies	85% ± 11%	Explore
retinal pigment epithelial cell	3 studies	33% ± 11%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC26A7 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	48914.70	652 / 653	84%	99.15	507 / 605
kidney	100%	3140.34	89 / 89	21%	24.11	187 / 901
breast	92%	144.76	424 / 459	12%	0.54	129 / 1118
ureter	0%	0	0 / 0	100%	6.66	1 / 1
stomach	91%	533.44	327 / 359	5%	0.11	13 / 286
bladder	90%	39.05	19 / 21	5%	0.16	24 / 504
adipose	91%	141.65	1097 / 1204	0%	0	0 / 0
uterus	72%	180.14	122 / 170	18%	4.69	84 / 459
adrenal gland	87%	55.46	225 / 258	3%	0.08	6 / 230
intestine	84%	63.92	808 / 966	4%	0.10	20 / 527
spleen	83%	49.41	200 / 241	0%	0	0 / 0
skin	69%	75.52	1255 / 1809	11%	0.30	50 / 472
prostate	78%	49.98	192 / 245	1%	0.02	6 / 502
pancreas	71%	113.42	233 / 328	6%	0.08	11 / 178
ovary	29%	19.86	53 / 180	47%	2.73	203 / 430
blood vessel	76%	57.59	1008 / 1335	0%	0	0 / 0
lung	69%	45.72	397 / 578	5%	0.14	52 / 1155
heart	60%	64.54	519 / 861	0%	0	0 / 0
esophagus	48%	24.33	688 / 1445	7%	0.19	13 / 183
muscle	54%	28.25	435 / 803	0%	0	0 / 0
brain	22%	13.20	571 / 2642	15%	0.51	107 / 705
liver	24%	10.85	55 / 226	1%	0.03	6 / 406
peripheral blood	7%	3.30	67 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.04	1 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45

GO_0006590	Biological process	thyroid hormone generation
GO_0006821	Biological process	chloride transport
GO_0019532	Biological process	oxalate transport
GO_0006811	Biological process	monoatomic ion transport
GO_0035429	Biological process	gluconate transmembrane transport
GO_0015705	Biological process	iodide transport
GO_0015706	Biological process	nitrate transmembrane transport
GO_0008272	Biological process	sulfate transport
GO_1902476	Biological process	chloride transmembrane transport
GO_1902358	Biological process	sulfate transmembrane transport
GO_0001696	Biological process	gastric acid secretion
GO_0015701	Biological process	bicarbonate transport
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0055038	Cellular component	recycling endosome membrane
GO_0016328	Cellular component	lateral plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005768	Cellular component	endosome
GO_0016323	Cellular component	basolateral plasma membrane
GO_0019531	Molecular function	oxalate transmembrane transporter activity
GO_0015116	Molecular function	sulfate transmembrane transporter activity
GO_0015106	Molecular function	bicarbonate transmembrane transporter activity
GO_0015108	Molecular function	chloride transmembrane transporter activity
GO_0140900	Molecular function	chloride:bicarbonate antiporter activity
GO_0005254	Molecular function	chloride channel activity

Gene name	SLC26A7
Protein name	Solute carrier family 26 member 7 Anion exchange transporter (Solute carrier family 26 member 7) Solute carrier family 6 member 7
Synonyms	SUT2
Description	FUNCTION: Acts as an anion channel mediating the transport of chloride, sulfate and oxalate ions . Mediates the transport of bromide, iodide, nitrate, gluconate, thiocyanate and bicarbonate ions (By similarity). Its permeability towards bicarbonate is weak and increases when pH is above 7 (By similarity). Mediates thiocyanate transport in retinal pigment epithelium cells (By similarity). Mediates iodide transport in the thyroid gland, playing an important role in the synthesis of thyroid hormones and the maintenance of thyroid function . Although it is an anion channel, according to PubMed:12736153 and PubMed:32119864 it has been shown to exhibit chloride-bicarbonate exchanger activity. .
Accessions	ENST00000309536.6 [Q8TE54-2] E5RGL8 ENST00000522181.5 ENST00000617078.3 A0A087WZI7 ENST00000520818.5 ENST00000522862.5 Q8TE54 A0A5P9KGI1 ENST00000523719.5 [Q8TE54-1] ENST00000617233.2 [Q8TE54-1] H0YB61 ENST00000276609.8 [Q8TE54-1] E5RFH2

SLC26A7 report