I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 20% ± 6% | |
| GABAergic neuron | 3 studies | 22% ± 1% | |
| glutamatergic neuron | 3 studies | 28% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 20% ± 6% | |
| GABAergic neuron | 3 studies | 22% ± 1% | |
| glutamatergic neuron | 3 studies | 28% ± 2% |
Insufficient scRNA-seq data for expression of SLC25A44 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1813.36 | 1445 / 1445 | 100% | 25.86 | 183 / 183 |
| intestine | 100% | 2106.93 | 966 / 966 | 100% | 15.83 | 527 / 527 |
| liver | 100% | 3246.27 | 226 / 226 | 100% | 26.90 | 406 / 406 |
| stomach | 100% | 1799.71 | 359 / 359 | 100% | 18.01 | 286 / 286 |
| uterus | 100% | 1837.81 | 170 / 170 | 100% | 19.58 | 459 / 459 |
| lung | 100% | 2560.04 | 578 / 578 | 100% | 22.17 | 1154 / 1155 |
| brain | 100% | 3147.68 | 2638 / 2642 | 100% | 33.77 | 705 / 705 |
| breast | 100% | 2035.29 | 459 / 459 | 100% | 29.77 | 1115 / 1118 |
| skin | 100% | 2190.27 | 1809 / 1809 | 100% | 29.12 | 470 / 472 |
| bladder | 100% | 1740.10 | 21 / 21 | 99% | 17.45 | 501 / 504 |
| prostate | 100% | 1974.05 | 245 / 245 | 99% | 15.81 | 498 / 502 |
| thymus | 100% | 2331.30 | 653 / 653 | 99% | 16.69 | 600 / 605 |
| kidney | 100% | 3595.28 | 89 / 89 | 98% | 20.09 | 887 / 901 |
| ovary | 98% | 1436.90 | 177 / 180 | 100% | 19.24 | 429 / 430 |
| pancreas | 97% | 960.57 | 318 / 328 | 99% | 16.13 | 176 / 178 |
| adrenal gland | 100% | 2004.12 | 258 / 258 | 94% | 16.49 | 216 / 230 |
| adipose | 100% | 2702.53 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.86 | 29 / 29 |
| spleen | 100% | 3271.42 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 19.47 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.15 | 1 / 1 |
| muscle | 100% | 1849.35 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1647.58 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 5943.86 | 918 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 18.27 | 79 / 80 |
| heart | 97% | 1468.93 | 835 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006865 | Biological process | amino acid transport |
| GO_0120161 | Biological process | regulation of cold-induced thermogenesis |
| GO_0009083 | Biological process | branched-chain amino acid catabolic process |
| GO_0015803 | Biological process | branched-chain amino acid transport |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0031966 | Cellular component | mitochondrial membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0015658 | Molecular function | branched-chain amino acid transmembrane transporter activity |
| Gene name | SLC25A44 |
| Protein name | Solute carrier family 25 member 44 |
| Synonyms | KIAA0446 |
| Description | FUNCTION: Mitochondrial solute transporter which transports branched-chain amino acid (BCAA; valine, leucine and isoleucine) into mitochondria in brown adipose tissue (BAT) (By similarity). BAT is involved in BCAA catabolism and actively utilizes BCAA in the mitochondria for thermogenesis . . |
| Accessions | A0A804HJB0 ENST00000359511.5 ENST00000423538.6 ENST00000684582.1 Q96H78 E9PGQ0 |
