SLC25A14 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC25A14 at tissue level.

III. Associated gene sets

GO_1902600Biological processproton transmembrane transport
GO_0009060Biological processaerobic respiration
GO_1902476Biological processchloride transmembrane transport
GO_1900407Biological processregulation of cellular response to oxidative stress
GO_0015698Biological processinorganic anion transport
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005886Cellular componentplasma membrane
GO_0005739Cellular componentmitochondrion
GO_0042803Molecular functionprotein homodimerization activity
GO_0015078Molecular functionproton transmembrane transporter activity
GO_0005452Molecular functionsolute:inorganic anion antiporter activity
GO_0022857Molecular functiontransmembrane transporter activity
GO_0015108Molecular functionchloride transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC25A14
Protein nameBrain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14)
Solute carrier family 25 member 14
SynonymsUCP5
UNQ791/PRO1682
BMCP1
DescriptionFUNCTION: Transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate and glutamate and tricarboxylates . May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also can mediate a very low unidirectional transport of anions including sulfate, phosphate, (S)-malate, citrate, L-aspartate and L-glutamate . Maintains oxidative balance (through uncoupling activities) and ATP production (by modifying mitochondrial membrane potential) . Is able to transport protons across lipid membranes . Also exhibits transmembrane chloride transport activity to a lesser extent. May modify mitochondrial respiratory efficiency and mitochondrial oxidant production (By similarity). .

AccessionsENST00000545805.6 [O95258-1]
O95258
Q5JY88
ENST00000424447.5
ENST00000361980.9 [O95258-2]
ENST00000543953.5
ENST00000339231.3 [O95258-3]
F6SL11
ENST00000218197.9 [O95258-1]
ENST00000612248.4 [O95258-3]