Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 4 studies | 24% ± 7% | |
| GABAergic neuron | 3 studies | 22% ± 2% | |
| glutamatergic neuron | 3 studies | 30% ± 3% |
Insufficient scRNA-seq data for expression of SLC25A14 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 549.69 | 258 / 258 | 100% | 14.80 | 230 / 230 |
| esophagus | 100% | 457.30 | 1445 / 1445 | 100% | 7.45 | 183 / 183 |
| prostate | 100% | 636.49 | 245 / 245 | 100% | 8.35 | 502 / 502 |
| uterus | 100% | 699.21 | 170 / 170 | 100% | 12.14 | 459 / 459 |
| breast | 100% | 500.49 | 459 / 459 | 100% | 11.40 | 1116 / 1118 |
| brain | 100% | 1020.84 | 2637 / 2642 | 100% | 14.03 | 705 / 705 |
| ovary | 100% | 690.38 | 180 / 180 | 100% | 8.26 | 429 / 430 |
| intestine | 100% | 520.04 | 966 / 966 | 100% | 8.61 | 525 / 527 |
| bladder | 100% | 483.76 | 21 / 21 | 100% | 10.00 | 502 / 504 |
| thymus | 100% | 801.85 | 653 / 653 | 100% | 8.14 | 602 / 605 |
| skin | 100% | 536.25 | 1809 / 1809 | 99% | 10.00 | 469 / 472 |
| lung | 99% | 460.03 | 574 / 578 | 100% | 9.15 | 1155 / 1155 |
| kidney | 100% | 523.45 | 89 / 89 | 99% | 7.05 | 891 / 901 |
| pancreas | 99% | 404.69 | 326 / 328 | 99% | 10.06 | 177 / 178 |
| stomach | 100% | 434.86 | 359 / 359 | 99% | 8.05 | 282 / 286 |
| liver | 99% | 225.50 | 223 / 226 | 87% | 4.22 | 355 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 10.61 | 29 / 29 |
| spleen | 100% | 563.85 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 10.25 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.27 | 1 / 1 |
| adipose | 100% | 386.66 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 501.89 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| heart | 95% | 276.35 | 819 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 4.95 | 76 / 80 |
| muscle | 89% | 206.82 | 711 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 64% | 190.14 | 593 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1902600 | Biological process | proton transmembrane transport |
| GO_0009060 | Biological process | aerobic respiration |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_1900407 | Biological process | regulation of cellular response to oxidative stress |
| GO_0015698 | Biological process | inorganic anion transport |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0015078 | Molecular function | proton transmembrane transporter activity |
| GO_0005452 | Molecular function | solute:inorganic anion antiporter activity |
| GO_0022857 | Molecular function | transmembrane transporter activity |
| GO_0015108 | Molecular function | chloride transmembrane transporter activity |
| Gene name | SLC25A14 |
| Protein name | Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Solute carrier family 25 member 14 |
| Synonyms | UCP5 UNQ791/PRO1682 BMCP1 |
| Description | FUNCTION: Transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate and glutamate and tricarboxylates . May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also can mediate a very low unidirectional transport of anions including sulfate, phosphate, (S)-malate, citrate, L-aspartate and L-glutamate . Maintains oxidative balance (through uncoupling activities) and ATP production (by modifying mitochondrial membrane potential) . Is able to transport protons across lipid membranes . Also exhibits transmembrane chloride transport activity to a lesser extent. May modify mitochondrial respiratory efficiency and mitochondrial oxidant production (By similarity). . |
| Accessions | ENST00000545805.6 [O95258-1] O95258 Q5JY88 ENST00000424447.5 ENST00000361980.9 [O95258-2] ENST00000543953.5 ENST00000339231.3 [O95258-3] F6SL11 ENST00000218197.9 [O95258-1] ENST00000612248.4 [O95258-3] |