Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retinal cone cell | 7 studies | 45% ± 12% | |
| non-classical monocyte | 6 studies | 25% ± 9% | |
| astrocyte | 6 studies | 36% ± 20% | |
| GABAergic neuron | 5 studies | 27% ± 6% | |
| classical monocyte | 4 studies | 25% ± 7% | |
| retinal bipolar neuron | 4 studies | 45% ± 12% | |
| glutamatergic neuron | 4 studies | 32% ± 7% | |
| OFF-bipolar cell | 3 studies | 37% ± 11% | |
| rod bipolar cell | 3 studies | 59% ± 2% | |
| monocyte | 3 studies | 18% ± 3% | |
| interneuron | 3 studies | 30% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 89% | 1087.57 | 2350 / 2642 | 77% | 6.47 | 540 / 705 |
| spleen | 100% | 1429.87 | 241 / 241 | 0% | 0 | 0 / 0 |
| lung | 96% | 487.40 | 552 / 578 | 2% | 0.06 | 25 / 1155 |
| peripheral blood | 81% | 1723.53 | 753 / 929 | 0% | 0 | 0 / 0 |
| adipose | 53% | 147.51 | 634 / 1204 | 0% | 0 | 0 / 0 |
| esophagus | 44% | 140.17 | 637 / 1445 | 1% | 0.02 | 2 / 183 |
| blood vessel | 43% | 348.89 | 576 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 38% | 93.02 | 98 / 258 | 3% | 0.12 | 8 / 230 |
| skin | 3% | 6.87 | 57 / 1809 | 36% | 3.18 | 171 / 472 |
| intestine | 39% | 102.40 | 372 / 966 | 0% | 0.01 | 2 / 527 |
| prostate | 32% | 97.16 | 78 / 245 | 0% | 0.01 | 2 / 502 |
| ovary | 26% | 67.96 | 47 / 180 | 0% | 0.00 | 1 / 430 |
| stomach | 20% | 58.98 | 73 / 359 | 1% | 0.01 | 3 / 286 |
| muscle | 18% | 51.83 | 148 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 16% | 0.32 | 13 / 80 |
| bladder | 14% | 32.86 | 3 / 21 | 0% | 0.00 | 2 / 504 |
| breast | 14% | 35.31 | 65 / 459 | 0% | 0.01 | 2 / 1118 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.25 | 4 / 29 |
| heart | 12% | 27.21 | 102 / 861 | 0% | 0 | 0 / 0 |
| uterus | 8% | 17.46 | 14 / 170 | 1% | 0.04 | 6 / 459 |
| kidney | 3% | 5.82 | 3 / 89 | 2% | 0.02 | 15 / 901 |
| thymus | 3% | 6.49 | 19 / 653 | 0% | 0.00 | 2 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.02 | 1 / 45 |
| liver | 2% | 4.51 | 5 / 226 | 0% | 0 | 0 / 406 |
| pancreas | 1% | 2.22 | 3 / 328 | 1% | 0.02 | 2 / 178 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0055074 | Biological process | calcium ion homeostasis |
| GO_0042756 | Biological process | drinking behavior |
| GO_0036368 | Biological process | cone photoresponse recovery |
| GO_1990834 | Biological process | response to odorant |
| GO_0007602 | Biological process | phototransduction |
| GO_0009644 | Biological process | response to high light intensity |
| GO_0006811 | Biological process | monoatomic ion transport |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0098703 | Biological process | calcium ion import across plasma membrane |
| GO_0050911 | Biological process | detection of chemical stimulus involved in sensory perception of smell |
| GO_0007608 | Biological process | sensory perception of smell |
| GO_0006874 | Biological process | intracellular calcium ion homeostasis |
| GO_0071805 | Biological process | potassium ion transmembrane transport |
| GO_0071486 | Biological process | cellular response to high light intensity |
| GO_1990680 | Biological process | response to melanocyte-stimulating hormone |
| GO_0008277 | Biological process | regulation of G protein-coupled receptor signaling pathway |
| GO_0021630 | Biological process | olfactory nerve maturation |
| GO_0050849 | Biological process | negative regulation of calcium-mediated signaling |
| GO_0070166 | Biological process | enamel mineralization |
| GO_1990034 | Biological process | calcium ion export across plasma membrane |
| GO_0086009 | Biological process | membrane repolarization |
| GO_0097186 | Biological process | amelogenesis |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_1903998 | Biological process | regulation of eating behavior |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0120199 | Cellular component | cone photoreceptor outer segment |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0031982 | Cellular component | vesicle |
| GO_0015293 | Molecular function | symporter activity |
| GO_0048306 | Molecular function | calcium-dependent protein binding |
| GO_0008273 | Molecular function | calcium, potassium:sodium antiporter activity |
| GO_0005516 | Molecular function | calmodulin binding |
| GO_0005262 | Molecular function | calcium channel activity |
| Gene name | SLC24A4 |
| Protein name | Solute carrier family 24 member 4 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) |
| Synonyms | NCKX4 |
| Description | FUNCTION: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) . Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived (By similarity). May play a role in calcium transport during amelogenesis . . |
| Accessions | H0YCX3 ENST00000554461.5 ENST00000676001.1 [Q8NFF2-1] ENST00000531433.5 [Q8NFF2-3] ENST00000393265.6 [Q8NFF2-2] ENST00000525557.5 ENST00000532405.6 [Q8NFF2-1] G3V505 Q8NFF2 |