Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 3 studies | 35% ± 12% |
Insufficient scRNA-seq data for expression of SLC17A4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 3941.30 | 225 / 226 | 93% | 30.70 | 378 / 406 |
| pancreas | 100% | 2133.84 | 328 / 328 | 46% | 4.42 | 81 / 178 |
| kidney | 84% | 492.37 | 75 / 89 | 61% | 25.36 | 551 / 901 |
| intestine | 52% | 1488.42 | 504 / 966 | 38% | 2.82 | 200 / 527 |
| stomach | 1% | 0.80 | 2 / 359 | 28% | 2.12 | 81 / 286 |
| esophagus | 0% | 1.11 | 4 / 1445 | 19% | 2.11 | 34 / 183 |
| bladder | 0% | 0 | 0 / 21 | 10% | 0.58 | 51 / 504 |
| prostate | 0% | 0 | 0 / 245 | 6% | 0.66 | 28 / 502 |
| lung | 0% | 0 | 0 / 578 | 4% | 0.39 | 44 / 1155 |
| brain | 2% | 2.05 | 43 / 2642 | 0% | 0 | 0 / 705 |
| uterus | 0% | 0 | 0 / 170 | 2% | 0.15 | 7 / 459 |
| adrenal gland | 0% | 0 | 0 / 258 | 1% | 0.79 | 2 / 230 |
| breast | 0% | 4.24 | 2 / 459 | 0% | 0.02 | 2 / 1118 |
| adipose | 1% | 0.82 | 7 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 0% | 2.07 | 1 / 241 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0.02 | 1 / 430 |
| peripheral blood | 0% | 0.20 | 2 / 929 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.10 | 1 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.09 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| skin | 0% | 0 | 0 / 1809 | 0% | 0 | 0 / 472 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0 | 0 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006796 | Biological process | phosphate-containing compound metabolic process |
| GO_0006820 | Biological process | monoatomic anion transport |
| GO_0044341 | Biological process | sodium-dependent phosphate transport |
| GO_0015747 | Biological process | urate transport |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0070327 | Biological process | thyroid hormone transport |
| GO_0031526 | Cellular component | brush border membrane |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0015349 | Molecular function | thyroid hormone transmembrane transporter activity |
| GO_0022857 | Molecular function | transmembrane transporter activity |
| GO_0015143 | Molecular function | urate transmembrane transporter activity |
| GO_0005436 | Molecular function | sodium:phosphate symporter activity |
| Gene name | SLC17A4 |
| Protein name | Probable small intestine urate exporter (Solute carrier family 17 member 4) |
| Synonyms | |
| Description | FUNCTION: Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions . Mediates chloride-dependent transport of urate . Mediates sodium-independent high affinity transport of thyroid hormones including L-thyroxine (T4) and 3,3',5-triiodo-L-thyronine (T3) . Can actively transport inorganic phosphate into cells via Na(+) cotransport . . |
| Accessions | ENST00000377905.9 [Q9Y2C5-1] ENST00000397076.2 [Q9Y2C5-4] Q9Y2C5 ENST00000439485.6 [Q9Y2C5-2] |