SLC17A4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC17A4 at tissue level.

III. Associated gene sets

GO_0006796Biological processphosphate-containing compound metabolic process
GO_0006820Biological processmonoatomic anion transport
GO_0044341Biological processsodium-dependent phosphate transport
GO_0015747Biological processurate transport
GO_0006814Biological processsodium ion transport
GO_0035725Biological processsodium ion transmembrane transport
GO_0070327Biological processthyroid hormone transport
GO_0031526Cellular componentbrush border membrane
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0015349Molecular functionthyroid hormone transmembrane transporter activity
GO_0022857Molecular functiontransmembrane transporter activity
GO_0015143Molecular functionurate transmembrane transporter activity
GO_0005436Molecular functionsodium:phosphate symporter activity

IV. Literature review

[source]
Gene nameSLC17A4
Protein nameProbable small intestine urate exporter (Solute carrier family 17 member 4)
Synonyms
DescriptionFUNCTION: Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions . Mediates chloride-dependent transport of urate . Mediates sodium-independent high affinity transport of thyroid hormones including L-thyroxine (T4) and 3,3',5-triiodo-L-thyronine (T3) . Can actively transport inorganic phosphate into cells via Na(+) cotransport . .

AccessionsENST00000377905.9 [Q9Y2C5-1]
ENST00000397076.2 [Q9Y2C5-4]
Q9Y2C5
ENST00000439485.6 [Q9Y2C5-2]