SLC17A3 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell of proximal tubule	7 studies	28% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC17A3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	6667.02	89 / 89	82%	178.72	743 / 901
liver	100%	1331.71	226 / 226	58%	8.25	237 / 406
adrenal gland	95%	73.95	244 / 258	2%	0.13	4 / 230
ovary	91%	34.16	163 / 180	0%	0	0 / 430
lung	75%	8.93	436 / 578	0%	0.02	4 / 1155
spleen	64%	7.07	155 / 241	0%	0	0 / 0
prostate	60%	8.24	147 / 245	0%	0	0 / 502
blood vessel	50%	7.53	671 / 1335	0%	0	0 / 0
uterus	49%	4.46	84 / 170	0%	0	0 / 459
heart	48%	6.37	413 / 861	0%	0	0 / 0
intestine	40%	3.34	383 / 966	0%	0	0 / 527
adipose	39%	3.41	475 / 1204	0%	0	0 / 0
bladder	38%	2.48	8 / 21	0%	0.01	1 / 504
peripheral blood	37%	3.99	345 / 929	0%	0	0 / 0
thymus	37%	2.70	242 / 653	0%	0	0 / 605
breast	34%	2.56	155 / 459	0%	0.04	4 / 1118
stomach	22%	1.33	80 / 359	0%	0	0 / 286
brain	17%	1.05	460 / 2642	0%	0	0 / 705
pancreas	17%	0.93	56 / 328	0%	0	0 / 178
esophagus	17%	1.05	240 / 1445	0%	0	0 / 183
skin	8%	0.49	143 / 1809	0%	0	0 / 472
muscle	5%	0.30	44 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0046415	Biological process	urate metabolic process
GO_0098656	Biological process	monoatomic anion transmembrane transport
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_1990961	Biological process	xenobiotic detoxification by transmembrane export across the plasma membrane
GO_0015747	Biological process	urate transport
GO_0006820	Biological process	monoatomic anion transport
GO_0006814	Biological process	sodium ion transport
GO_0015711	Biological process	organic anion transport
GO_0015760	Biological process	glucose-6-phosphate transport
GO_0006817	Biological process	phosphate ion transport
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0031526	Cellular component	brush border membrane
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005737	Cellular component	cytoplasm
GO_0008514	Molecular function	organic anion transmembrane transporter activity
GO_0015562	Molecular function	efflux transmembrane transporter activity
GO_0015143	Molecular function	urate transmembrane transporter activity
GO_0005436	Molecular function	sodium:phosphate symporter activity
GO_0008308	Molecular function	voltage-gated monoatomic anion channel activity
GO_0019534	Molecular function	toxin transmembrane transporter activity
GO_0042910	Molecular function	xenobiotic transmembrane transporter activity

Gene name	SLC17A3
Protein name	Solute carrier family 17 member 3 Sodium-dependent phosphate transport protein 4 (Na(+)/PI cotransporter 4) (NPT4) (Sodium/phosphate cotransporter 4) (Solute carrier family 17 member 3)
Synonyms	NPT4
Description	FUNCTION: [Isoform 2]: Transports organic anions in a voltage-driven, multispecific, manner, on the apical side of renal proximal tubule . In particular, participates in the secretion of urate from the cell into the lumen . Urate is the end product of purine metabolism . May have roles in the metabolism and secretion of estrone sulfate, estradiol-17-beta-glucuronide, ochratoxin A, as wells as drugs such as bumetanide . .
Accessions	H0Y9F7 ENST00000360657.7 [O00476-1] E9PBQ8 ENST00000481949.6 ENST00000505420.5 ENST00000449356.2 ENST00000361703.10 [O00476-1] H0Y8R7 ENST00000506105.5 ENST00000397060.8 [O00476-2] O00476

SLC17A3 report