I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal pigment epithelial cell | 4 studies | 56% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retinal pigment epithelial cell | 4 studies | 56% ± 10% |
Insufficient scRNA-seq data for expression of SLC16A8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 98% | 413.32 | 241 / 245 | 85% | 4.55 | 427 / 502 |
| uterus | 93% | 91.16 | 158 / 170 | 76% | 4.92 | 350 / 459 |
| brain | 99% | 227.19 | 2625 / 2642 | 65% | 1.77 | 459 / 705 |
| esophagus | 83% | 58.49 | 1206 / 1445 | 79% | 2.90 | 145 / 183 |
| ovary | 88% | 68.32 | 159 / 180 | 74% | 3.42 | 318 / 430 |
| breast | 95% | 159.86 | 438 / 459 | 58% | 1.74 | 647 / 1118 |
| thymus | 100% | 178.42 | 653 / 653 | 52% | 1.13 | 316 / 605 |
| lung | 90% | 93.55 | 521 / 578 | 61% | 2.27 | 708 / 1155 |
| pancreas | 83% | 60.16 | 271 / 328 | 69% | 1.71 | 122 / 178 |
| kidney | 94% | 83.65 | 84 / 89 | 46% | 1.26 | 415 / 901 |
| adrenal gland | 79% | 52.10 | 205 / 258 | 61% | 2.22 | 140 / 230 |
| bladder | 81% | 85.05 | 17 / 21 | 47% | 1.73 | 235 / 504 |
| stomach | 84% | 61.99 | 303 / 359 | 37% | 0.94 | 105 / 286 |
| skin | 75% | 104.96 | 1354 / 1809 | 40% | 1.99 | 191 / 472 |
| intestine | 83% | 56.90 | 805 / 966 | 28% | 0.73 | 150 / 527 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.85 | 1 / 1 |
| blood vessel | 98% | 183.87 | 1308 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 95% | 99.85 | 1142 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 85% | 70.73 | 204 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 3.79 | 38 / 45 |
| eye | 0% | 0 | 0 / 0 | 84% | 4.69 | 67 / 80 |
| heart | 71% | 57.98 | 615 / 861 | 0% | 0 | 0 / 0 |
| liver | 48% | 26.42 | 109 / 226 | 17% | 0.54 | 71 / 406 |
| muscle | 61% | 41.54 | 493 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.22 | 2 / 29 |
| peripheral blood | 2% | 0.97 | 21 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015718 | Biological process | monocarboxylic acid transport |
| GO_0015727 | Biological process | lactate transport |
| GO_0035873 | Biological process | lactate transmembrane transport |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0015293 | Molecular function | symporter activity |
| GO_0015129 | Molecular function | lactate transmembrane transporter activity |
| GO_0008028 | Molecular function | monocarboxylic acid transmembrane transporter activity |
| Gene name | SLC16A8 |
| Protein name | Monocarboxylate transporter 3 (MCT 3) (Solute carrier family 16 member 8) |
| Synonyms | MCT3 |
| Description | FUNCTION: Probable retinal pigment epithelium (RPE)-specific proton-coupled L-lactate transporter (By similarity). May facilitate transport of lactate and H(+) out of the retina and could therefore play a role in pH and ion homeostasis of the outer retina (By similarity). . |
| Accessions | ENST00000681075.2 ENST00000320521.10 O95907 |
