SLC15A1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC15A1 at tissue level.

III. Associated gene sets

GO_0006811Biological processmonoatomic ion transport
GO_0015031Biological processprotein transport
GO_0140206Biological processdipeptide import across plasma membrane
GO_0015833Biological processpeptide transport
GO_0140207Biological processtripeptide import across plasma membrane
GO_1902600Biological processproton transmembrane transport
GO_0005903Cellular componentbrush border
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0042937Molecular functiontripeptide transmembrane transporter activity
GO_0071916Molecular functiondipeptide transmembrane transporter activity
GO_0005427Molecular functionproton-dependent oligopeptide secondary active transmembrane transporter activity
GO_0015333Molecular functionpeptide:proton symporter activity

IV. Literature review

[source]
Gene nameSLC15A1
Protein nameSolute carrier family 15 member 1 (Intestinal H(+)/peptide cotransporter) (Oligopeptide transporter, small intestine isoform) (Peptide transporter 1)
SynonymsPEPT1
DescriptionFUNCTION: Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1 (By similarity). Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (By similarity). Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system . .

AccessionsENST00000376503.10
Q4VAL9
P46059