SLC12A1 | OmnibusX

Name	Number of supported studies	Average coverage
kidney loop of Henle epithelial cell	8 studies	71% ± 22%	Explore
glutamatergic neuron	3 studies	28% ± 1%	Explore

Name	Number of supported studies	Average coverage
kidney	4 studies	29% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	19777.93	89 / 89	23%	3.48	203 / 901
adrenal gland	93%	30.12	239 / 258	6%	0.14	14 / 230
brain	90%	76.28	2372 / 2642	0%	0.01	3 / 705
ovary	40%	5.73	72 / 180	14%	0.59	59 / 430
liver	35%	12.14	79 / 226	11%	0.57	43 / 406
blood vessel	44%	24.46	593 / 1335	0%	0	0 / 0
breast	27%	5.25	122 / 459	11%	0.46	126 / 1118
spleen	27%	6.43	64 / 241	0%	0	0 / 0
adipose	25%	4.57	301 / 1204	0%	0	0 / 0
prostate	18%	3.13	43 / 245	4%	0.09	22 / 502
peripheral blood	22%	15.96	200 / 929	0%	0	0 / 0
lung	15%	2.40	85 / 578	1%	0.01	6 / 1155
stomach	14%	2.47	50 / 359	1%	0.01	2 / 286
intestine	13%	1.88	127 / 966	0%	0.00	1 / 527
skin	12%	1.83	212 / 1809	0%	0.01	2 / 472
esophagus	10%	1.55	146 / 1445	0%	0	0 / 183
bladder	10%	1.81	2 / 21	0%	0	0 / 504
uterus	7%	0.94	12 / 170	1%	0.03	6 / 459
muscle	6%	0.78	47 / 803	0%	0	0 / 0
pancreas	4%	0.50	13 / 328	0%	0	0 / 178
thymus	4%	0.43	23 / 653	0%	0	0 / 605
heart	3%	0.53	28 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.12	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0055078	Biological process	sodium ion homeostasis
GO_0006811	Biological process	monoatomic ion transport
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0055064	Biological process	chloride ion homeostasis
GO_1902476	Biological process	chloride transmembrane transport
GO_0006884	Biological process	cell volume homeostasis
GO_0055075	Biological process	potassium ion homeostasis
GO_0035725	Biological process	sodium ion transmembrane transport
GO_1990573	Biological process	potassium ion import across plasma membrane
GO_0016324	Cellular component	apical plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0008511	Molecular function	sodium:potassium:chloride symporter activity

Gene name	SLC12A1
Protein name	Solute carrier family 12 member 1 Solute carrier family 12 member 1 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter) SLC12A1 protein (Solute carrier family 12 member 1) Alternative protein SLC12A1
Synonyms	NKCC2
Description	FUNCTION: Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation . Electrically silent transporter system (By similarity). .
Accessions	A0A8I5KSK6 Q13621 ENST00000380993.8 [Q13621-1] ENST00000330289.10 A0A2R8Y6V7 H0YLJ2 ENST00000686073.1 H0YMG9 ENST00000561127.5 H0YNW0 ENST00000561031.1 ENST00000646012.1 ENST00000396577.7 [Q13621-3] ENST00000647232.1 [Q13621-3] ENST00000647546.1 [Q13621-1] Q8IUN5 L8E9E3 ENST00000559641.5

SLC12A1 report