Insufficient scRNA-seq data for expression of SHPK at single-cell level.
Insufficient scRNA-seq data for expression of SHPK at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1029.60 | 1444 / 1445 | 100% | 4.14 | 183 / 183 |
| thymus | 100% | 1086.80 | 653 / 653 | 100% | 4.43 | 604 / 605 |
| liver | 100% | 2153.20 | 226 / 226 | 100% | 3.67 | 405 / 406 |
| kidney | 100% | 1452.85 | 89 / 89 | 99% | 3.97 | 896 / 901 |
| prostate | 100% | 1096.46 | 245 / 245 | 99% | 3.74 | 499 / 502 |
| lung | 100% | 899.61 | 578 / 578 | 99% | 3.32 | 1143 / 1155 |
| breast | 100% | 1332.07 | 459 / 459 | 99% | 4.05 | 1106 / 1118 |
| intestine | 100% | 1071.55 | 966 / 966 | 99% | 3.74 | 521 / 527 |
| bladder | 100% | 1022.62 | 21 / 21 | 99% | 3.79 | 497 / 504 |
| uterus | 100% | 1087.12 | 170 / 170 | 98% | 3.96 | 450 / 459 |
| stomach | 100% | 1150.26 | 359 / 359 | 98% | 3.87 | 280 / 286 |
| skin | 100% | 1482.92 | 1809 / 1809 | 98% | 4.42 | 462 / 472 |
| pancreas | 100% | 1089.39 | 328 / 328 | 98% | 2.67 | 174 / 178 |
| adrenal gland | 100% | 1693.14 | 258 / 258 | 96% | 2.83 | 221 / 230 |
| ovary | 100% | 1337.18 | 180 / 180 | 96% | 2.79 | 412 / 430 |
| brain | 97% | 623.99 | 2566 / 2642 | 98% | 3.18 | 688 / 705 |
| adipose | 100% | 1241.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 3.67 | 29 / 29 |
| spleen | 100% | 785.59 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 3.92 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.95 | 1 / 1 |
| blood vessel | 100% | 762.59 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 544.31 | 832 / 861 | 0% | 0 | 0 / 0 |
| muscle | 94% | 385.26 | 755 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 4.94 | 75 / 80 |
| peripheral blood | 66% | 465.05 | 611 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006071 | Biological process | glycerol metabolic process |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0005975 | Biological process | carbohydrate metabolic process |
| GO_0016310 | Biological process | phosphorylation |
| GO_0006098 | Biological process | pentose-phosphate shunt |
| GO_0043030 | Biological process | regulation of macrophage activation |
| GO_0035963 | Biological process | cellular response to interleukin-13 |
| GO_0009052 | Biological process | pentose-phosphate shunt, non-oxidative branch |
| GO_0050727 | Biological process | regulation of inflammatory response |
| GO_0071353 | Biological process | cellular response to interleukin-4 |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0050277 | Molecular function | sedoheptulokinase activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | SHPK |
| Protein name | Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein) |
| Synonyms | CARKL |
| Description | FUNCTION: Acts as a modulator of macrophage activation through control of glucose metabolism. . |
| Accessions | ENST00000225519.5 Q9UHJ6 |