SHOC1 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	6 studies	30% ± 15%	Explore
microglial cell	5 studies	29% ± 9%	Explore
macrophage	5 studies	24% ± 5%	Explore
adipocyte	4 studies	31% ± 8%	Explore
glutamatergic neuron	4 studies	29% ± 15%	Explore
endothelial cell	4 studies	17% ± 1%	Explore
oligodendrocyte precursor cell	4 studies	29% ± 7%	Explore
GABAergic neuron	3 studies	34% ± 14%	Explore
interneuron	3 studies	47% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	30% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
uterus	78%	17.56	133 / 170	55%	1.97	252 / 459
lung	90%	32.97	522 / 578	37%	1.42	425 / 1155
esophagus	64%	22.07	925 / 1445	55%	1.33	100 / 183
adrenal gland	99%	506.54	256 / 258	19%	4.29	43 / 230
kidney	100%	419.97	89 / 89	10%	1.47	87 / 901
spleen	98%	35.47	236 / 241	0%	0	0 / 0
bladder	76%	18.29	16 / 21	20%	0.71	99 / 504
skin	94%	80.62	1703 / 1809	1%	0.09	5 / 472
prostate	89%	29.43	218 / 245	1%	0.04	4 / 502
stomach	79%	57.11	284 / 359	7%	0.32	20 / 286
ovary	81%	20.47	146 / 180	4%	0.05	17 / 430
tonsil	0%	0	0 / 0	84%	2.43	38 / 45
thymus	74%	14.51	484 / 653	0%	0.00	1 / 605
peripheral blood	74%	69.01	688 / 929	0%	0	0 / 0
pancreas	62%	17.98	202 / 328	4%	0.20	8 / 178
breast	53%	10.88	245 / 459	5%	0.25	55 / 1118
intestine	50%	8.21	479 / 966	5%	0.15	24 / 527
adipose	44%	8.04	535 / 1204	0%	0	0 / 0
brain	42%	7.29	1097 / 2642	0%	0.01	2 / 705
liver	36%	5.39	81 / 226	1%	0.02	4 / 406
blood vessel	28%	4.46	371 / 1335	0%	0	0 / 0
heart	24%	3.69	207 / 861	0%	0	0 / 0
muscle	5%	1.18	38 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007131	Biological process	reciprocal meiotic recombination
GO_0007130	Biological process	synaptonemal complex assembly
GO_0000712	Biological process	resolution of meiotic recombination intermediates
GO_0000794	Cellular component	condensed nuclear chromosome
GO_0005694	Cellular component	chromosome
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0003697	Molecular function	single-stranded DNA binding

Gene name	SHOC1
Protein name	Shortage in chiasmata 1 Protein shortage in chiasmata 1 ortholog (EC 3.6.-.-) (Protein ZIP2 homolog) (MZIP2)
Synonyms	ZIP2 C9orf84
Description	FUNCTION: ATPase required during meiosis for the formation of crossover recombination intermediates (By similarity). Binds DNA: preferentially binds to single-stranded DNA and DNA branched structures . Does not show nuclease activity in vitro, but shows ATPase activity, which is stimulated by the presence of single-stranded DNA . Plays a key role in homologous recombination and crossing-over in meiotic prophase I in male and female germ cells (By similarity). Required for proper synaptonemal complex assembly and homologous chromosome pairing (By similarity). Requiref for recruitment TEX11 and MSH4 to recombination intermediates (By similarity). .
Accessions	ENST00000374283.5 [Q5VXU9-2] A0A804HJV9 A0A804HL92 ENST00000394777.8 ENST00000683745.1 A0A804HKR0 ENST00000318737.8 [Q5VXU9-1] A0A804HIH1 ENST00000394779.7 [Q5VXU9-3] Q5VXU9 ENST00000682672.1 A6PVK7 A0A804HLJ8 ENST00000374287.7 [Q5VXU9-1] ENST00000682571.1 ENST00000683944.1 ENST00000682961.1 A0A804HK82 ENST00000682074.1

SHOC1 report