Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 37% ± 21% | |
| astrocyte | 6 studies | 30% ± 8% | |
| neuron | 4 studies | 21% ± 3% | |
| oligodendrocyte precursor cell | 4 studies | 19% ± 3% | |
| epithelial cell | 4 studies | 22% ± 5% | |
| GABAergic neuron | 4 studies | 41% ± 14% | |
| endothelial cell | 3 studies | 37% ± 7% | |
| basal cell | 3 studies | 26% ± 4% | |
| ciliated cell | 3 studies | 19% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 31% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 12851.23 | 245 / 245 | 100% | 29.21 | 502 / 502 |
| thymus | 100% | 9800.04 | 653 / 653 | 100% | 21.90 | 603 / 605 |
| uterus | 100% | 6719.14 | 170 / 170 | 100% | 17.89 | 457 / 459 |
| esophagus | 100% | 6804.38 | 1445 / 1445 | 99% | 13.76 | 182 / 183 |
| brain | 100% | 11946.32 | 2630 / 2642 | 100% | 42.70 | 704 / 705 |
| skin | 100% | 5468.28 | 1807 / 1809 | 99% | 24.50 | 469 / 472 |
| breast | 100% | 7717.00 | 459 / 459 | 99% | 20.30 | 1107 / 1118 |
| kidney | 100% | 6956.91 | 89 / 89 | 97% | 16.03 | 877 / 901 |
| pancreas | 98% | 3179.96 | 323 / 328 | 98% | 15.60 | 174 / 178 |
| bladder | 100% | 6677.05 | 21 / 21 | 95% | 14.79 | 481 / 504 |
| lung | 100% | 6625.09 | 576 / 578 | 96% | 14.53 | 1104 / 1155 |
| ovary | 100% | 6112.62 | 180 / 180 | 94% | 11.61 | 405 / 430 |
| stomach | 100% | 5459.82 | 359 / 359 | 91% | 9.39 | 260 / 286 |
| adrenal gland | 100% | 6148.41 | 258 / 258 | 90% | 18.28 | 207 / 230 |
| intestine | 100% | 7060.31 | 966 / 966 | 89% | 8.88 | 468 / 527 |
| liver | 95% | 2385.54 | 214 / 226 | 64% | 6.24 | 259 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 39.52 | 80 / 80 |
| spleen | 100% | 8507.89 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.16 | 1 / 1 |
| blood vessel | 100% | 5133.99 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 4523.94 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 13.36 | 44 / 45 |
| heart | 97% | 3466.93 | 832 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 12.66 | 28 / 29 |
| muscle | 90% | 2349.86 | 722 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 86% | 2641.12 | 799 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0034499 | Biological process | late endosome to Golgi transport |
| GO_0090630 | Biological process | activation of GTPase activity |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042470 | Cellular component | melanosome |
| GO_0031267 | Molecular function | small GTPase binding |
| GO_0005096 | Molecular function | GTPase activator activity |
| Gene name | SGSM2 |
| Protein name | Small G protein signaling modulator 2 Small G protein signaling modulator 2 (RUN and TBC1 domain-containing protein 1) |
| Synonyms | KIAA0397 RUTBC1 |
| Description | FUNCTION: Possesses GTPase activator activity towards RAB32, RAB33B and RAB38 . Regulates the trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes by inactivating RAB32 and RAB38. Inhibits RAB32 and RAB38 activation both directly by promoting their GTPase activity and indirectly by disrupting the RAB9A-HPS4 interaction which is required for RAB32/38 activation . . |
| Accessions | V9GYD2 ENST00000573851.1 I3L361 ENST00000426855.6 [O43147-1] ENST00000268989.8 [O43147-2] ENST00000574563.5 [O43147-5] I3NI18 J3QSA2 ENST00000572925.1 ENST00000573062.5 ENST00000570431.1 I3L1Y7 V9GYJ0 ENST00000572875.1 O43147 ENST00000574650.1 |
