SERPINB7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SERPINB7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SERPINB7 at tissue level.

III. Associated gene sets

GO_0072126Biological processpositive regulation of glomerular mesangial cell proliferation
GO_0032914Biological processpositive regulation of transforming growth factor beta1 production
GO_0090362Biological processpositive regulation of platelet-derived growth factor production
GO_0032967Biological processpositive regulation of collagen biosynthetic process
GO_0010951Biological processnegative regulation of endopeptidase activity
GO_0005615Cellular componentextracellular space
GO_0005737Cellular componentcytoplasm
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity

IV. Literature review

[source]
Gene nameSERPINB7
Protein nameSerpin B7 (Megsin) (TP55)
Serpin family B member 7
Synonyms
DescriptionFUNCTION: Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.

AccessionsENST00000447428.5
ENST00000336429.6 [O75635-1]
C9JM00
C9JA68
ENST00000398019.7 [O75635-1]
O75635
ENST00000425392.5
A0A1B0GX82
ENST00000540675.5 [O75635-2]
ENST00000546027.5 [O75635-1]
ENST00000431370.1