I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 4 studies | 53% ± 21% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 4 studies | 53% ± 21% |
Insufficient scRNA-seq data for expression of SERPINA6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 12374.60 | 226 / 226 | 99% | 647.39 | 400 / 406 |
| kidney | 100% | 419.18 | 89 / 89 | 68% | 41.05 | 613 / 901 |
| pancreas | 100% | 516.04 | 328 / 328 | 54% | 37.41 | 96 / 178 |
| breast | 33% | 188.15 | 152 / 459 | 22% | 91.28 | 250 / 1118 |
| intestine | 31% | 51.01 | 303 / 966 | 12% | 4.90 | 62 / 527 |
| ovary | 23% | 7.55 | 42 / 180 | 2% | 0.52 | 8 / 430 |
| uterus | 18% | 20.15 | 31 / 170 | 3% | 1.48 | 16 / 459 |
| stomach | 4% | 1.04 | 13 / 359 | 11% | 7.90 | 32 / 286 |
| lung | 13% | 6.95 | 73 / 578 | 1% | 0.74 | 15 / 1155 |
| peripheral blood | 12% | 22.21 | 115 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 0% | 0.20 | 5 / 1445 | 4% | 1.53 | 8 / 183 |
| bladder | 0% | 0 | 0 / 21 | 3% | 0.95 | 15 / 504 |
| adrenal gland | 1% | 0.43 | 2 / 258 | 1% | 0.25 | 3 / 230 |
| prostate | 0% | 0.14 | 1 / 245 | 1% | 0.33 | 7 / 502 |
| adipose | 1% | 1.78 | 17 / 1204 | 0% | 0 | 0 / 0 |
| skin | 1% | 0.45 | 13 / 1809 | 0% | 0.02 | 1 / 472 |
| thymus | 1% | 0.18 | 4 / 653 | 0% | 0 | 0 / 605 |
| heart | 1% | 1.29 | 5 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 0.21 | 7 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 0% | 11.40 | 1 / 241 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.03 | 1 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.05 | 3 / 2642 | 0% | 0 | 0 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008211 | Biological process | glucocorticoid metabolic process |
| GO_0010951 | Biological process | negative regulation of endopeptidase activity |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0004867 | Molecular function | serine-type endopeptidase inhibitor activity |
| GO_0005496 | Molecular function | steroid binding |
| Gene name | SERPINA6 |
| Protein name | Corticosteroid-binding globulin (Serpin family A member 6) Corticosteroid-binding globulin (CBG) (Serpin A6) (Transcortin) Corticosteroid-binding globulin (Serpin family A member 6) (Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 6, isoform CRA_a) |
| Synonyms | CBG hCG_22332 |
| Description | FUNCTION: Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. . |
| Accessions | ENST00000557225.1 P08185 ENST00000341584.4 ENST00000631236.1 G3V4V7 G3V350 ENST00000555056.1 ENST00000621384.2 ENST00000630843.1 |
