Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 6 studies | 28% ± 11% | |
glutamatergic neuron | 5 studies | 48% ± 19% | |
astrocyte | 4 studies | 25% ± 6% | |
oligodendrocyte precursor cell | 4 studies | 24% ± 4% | |
interneuron | 4 studies | 39% ± 22% | |
endothelial cell | 3 studies | 20% ± 5% | |
GABAergic neuron | 3 studies | 55% ± 2% | |
neuron | 3 studies | 25% ± 6% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 42% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 2444.13 | 2642 / 2642 | 100% | 27.52 | 705 / 705 |
ovary | 100% | 925.02 | 180 / 180 | 99% | 9.90 | 426 / 430 |
breast | 99% | 613.44 | 455 / 459 | 99% | 9.71 | 1111 / 1118 |
bladder | 100% | 768.62 | 21 / 21 | 98% | 6.78 | 492 / 504 |
esophagus | 98% | 647.27 | 1417 / 1445 | 99% | 7.17 | 182 / 183 |
prostate | 100% | 1002.94 | 245 / 245 | 97% | 5.10 | 489 / 502 |
thymus | 100% | 811.53 | 652 / 653 | 97% | 5.60 | 589 / 605 |
uterus | 100% | 1069.92 | 170 / 170 | 97% | 7.76 | 444 / 459 |
lung | 99% | 657.34 | 574 / 578 | 97% | 6.65 | 1122 / 1155 |
intestine | 100% | 753.44 | 966 / 966 | 95% | 4.70 | 501 / 527 |
skin | 99% | 613.53 | 1799 / 1809 | 95% | 6.05 | 450 / 472 |
adrenal gland | 99% | 547.33 | 255 / 258 | 95% | 10.08 | 218 / 230 |
liver | 98% | 762.63 | 222 / 226 | 91% | 4.84 | 368 / 406 |
stomach | 95% | 497.02 | 340 / 359 | 94% | 5.22 | 269 / 286 |
kidney | 100% | 544.25 | 89 / 89 | 83% | 4.01 | 749 / 901 |
pancreas | 67% | 238.77 | 221 / 328 | 96% | 4.91 | 171 / 178 |
spleen | 100% | 917.62 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.77 | 1 / 1 |
blood vessel | 98% | 600.29 | 1314 / 1335 | 0% | 0 | 0 / 0 |
adipose | 98% | 533.41 | 1182 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 3.98 | 43 / 45 |
muscle | 95% | 485.46 | 765 / 803 | 0% | 0 | 0 / 0 |
heart | 93% | 666.28 | 800 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 84% | 793.08 | 779 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 83% | 6.07 | 24 / 29 |
eye | 0% | 0 | 0 / 0 | 66% | 2.98 | 53 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0031204 | Biological process | post-translational protein targeting to membrane, translocation |
GO_0006616 | Biological process | SRP-dependent cotranslational protein targeting to membrane, translocation |
GO_0008150 | Biological process | biological_process |
GO_0005784 | Cellular component | Sec61 translocon complex |
GO_0043022 | Molecular function | ribosome binding |
GO_0005048 | Molecular function | signal sequence binding |
GO_0008320 | Molecular function | protein transmembrane transporter activity |
GO_0003674 | Molecular function | molecular_function |
Gene name | SEC61A2 |
Protein name | Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2) SEC61 translocon subunit alpha 2 SEC61 translocon subunit alpha 2 (SEC61A2 protein) (Sec61 alpha 2 subunit (S. cerevisiae), isoform CRA_d) |
Synonyms | hCG_24888 |
Description | FUNCTION: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. . |
Accessions | H7C1S8 ENST00000298428.14 [Q9H9S3-1] H7C069 ENST00000457034.1 ENST00000379017.7 ENST00000379051.5 ENST00000379020.8 ENST00000441368.5 Q8TC24 Q9H9S3 ENST00000472221.5 ENST00000304267.12 [Q9H9S3-2] C9JJV4 H7C1Q9 ENST00000418772.1 F2Z2C7 ENST00000419021.1 A6NIF9 A6NK38 ENST00000379033.7 [Q9H9S3-3] F8W776 ENST00000475268.5 |