SEC61A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031204Biological processpost-translational protein targeting to membrane, translocation
GO_0006616Biological processSRP-dependent cotranslational protein targeting to membrane, translocation
GO_0008150Biological processbiological_process
GO_0005784Cellular componentSec61 translocon complex
GO_0043022Molecular functionribosome binding
GO_0005048Molecular functionsignal sequence binding
GO_0008320Molecular functionprotein transmembrane transporter activity
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameSEC61A2
Protein nameProtein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2)
SEC61 translocon subunit alpha 2
SEC61 translocon subunit alpha 2 (SEC61A2 protein) (Sec61 alpha 2 subunit (S. cerevisiae), isoform CRA_d)
SynonymshCG_24888
DescriptionFUNCTION: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. .

AccessionsH7C1S8
ENST00000298428.14 [Q9H9S3-1]
H7C069
ENST00000457034.1
ENST00000379017.7
ENST00000379051.5
ENST00000379020.8
ENST00000441368.5
Q8TC24
Q9H9S3
ENST00000472221.5
ENST00000304267.12 [Q9H9S3-2]
C9JJV4
H7C1Q9
ENST00000418772.1
F2Z2C7
ENST00000419021.1
A6NIF9
A6NK38
ENST00000379033.7 [Q9H9S3-3]
F8W776
ENST00000475268.5