I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 4 studies | 23% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 4 studies | 23% ± 5% |
Insufficient scRNA-seq data for expression of SDSL at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 1416.28 | 89 / 89 | 99% | 41.81 | 894 / 901 |
| thymus | 100% | 1458.30 | 653 / 653 | 99% | 51.99 | 597 / 605 |
| pancreas | 100% | 532.57 | 328 / 328 | 98% | 28.18 | 175 / 178 |
| adrenal gland | 100% | 1712.70 | 258 / 258 | 98% | 42.02 | 226 / 230 |
| liver | 100% | 3025.82 | 226 / 226 | 98% | 76.02 | 396 / 406 |
| prostate | 98% | 495.36 | 240 / 245 | 99% | 41.98 | 498 / 502 |
| brain | 95% | 442.72 | 2513 / 2642 | 99% | 35.79 | 699 / 705 |
| breast | 95% | 258.90 | 435 / 459 | 97% | 29.45 | 1079 / 1118 |
| ovary | 92% | 241.79 | 166 / 180 | 98% | 22.31 | 423 / 430 |
| stomach | 89% | 339.62 | 319 / 359 | 97% | 20.26 | 276 / 286 |
| intestine | 81% | 350.80 | 786 / 966 | 97% | 23.54 | 510 / 527 |
| lung | 93% | 342.49 | 538 / 578 | 85% | 17.65 | 982 / 1155 |
| bladder | 81% | 196.48 | 17 / 21 | 92% | 22.45 | 465 / 504 |
| uterus | 62% | 141.73 | 106 / 170 | 88% | 21.68 | 403 / 459 |
| skin | 43% | 95.50 | 784 / 1809 | 96% | 28.27 | 454 / 472 |
| esophagus | 69% | 151.68 | 1003 / 1445 | 60% | 7.45 | 109 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 17.14 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 22.62 | 79 / 80 |
| spleen | 98% | 316.70 | 236 / 241 | 0% | 0 | 0 / 0 |
| heart | 94% | 342.53 | 811 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 21.13 | 26 / 29 |
| adipose | 89% | 209.80 | 1071 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 81% | 222.24 | 1079 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 80% | 10.81 | 36 / 45 |
| peripheral blood | 47% | 92.07 | 437 / 929 | 0% | 0 | 0 / 0 |
| muscle | 35% | 67.11 | 285 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006565 | Biological process | L-serine catabolic process |
| GO_0006629 | Biological process | lipid metabolic process |
| GO_0008150 | Biological process | biological_process |
| GO_0009097 | Biological process | isoleucine biosynthetic process |
| GO_0006567 | Biological process | threonine catabolic process |
| GO_0005829 | Cellular component | cytosol |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0004794 | Molecular function | threonine deaminase activity |
| GO_0030170 | Molecular function | pyridoxal phosphate binding |
| GO_0003674 | Molecular function | molecular_function |
| GO_0003941 | Molecular function | L-serine ammonia-lyase activity |
| Gene name | SDSL |
| Protein name | L-serine ammonia-lyase (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) Serine dehydratase-like (L-serine deaminase) (L-serine dehydratase/L-threonine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) (Serine dehydratase 2) (SDH 2) (EC 4.3.1.17) Serine dehydratase like |
| Synonyms | |
| Description | FUNCTION: Has low serine dehydratase and threonine dehydratase activity. |
| Accessions | ENST00000553248.5 H0YID3 ENST00000547802.1 ENST00000345635.8 H0YIA2 ENST00000546672.1 F8VYZ3 ENST00000403593.9 ENST00000551760.1 Q96GA7 F8VZ97 |
