SCARA5 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of SCARA5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	88%	5984.60	851 / 966	56%	4.79	296 / 527
bladder	100%	14474.62	21 / 21	43%	2.69	219 / 504
stomach	86%	4257.59	307 / 359	54%	2.99	154 / 286
breast	92%	5698.80	423 / 459	44%	2.81	490 / 1118
esophagus	88%	8278.03	1269 / 1445	40%	3.85	73 / 183
thymus	83%	4311.70	545 / 653	35%	2.86	213 / 605
lung	74%	3773.94	427 / 578	45%	3.25	515 / 1155
skin	64%	3620.48	1152 / 1809	42%	3.57	200 / 472
adipose	98%	11380.11	1183 / 1204	0%	0	0 / 0
blood vessel	92%	7584.16	1227 / 1335	0%	0	0 / 0
heart	90%	7767.57	776 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	69%	5.40	20 / 29
prostate	30%	1427.03	74 / 245	28%	0.98	139 / 502
muscle	53%	1293.98	427 / 803	0%	0	0 / 0
ovary	43%	1734.46	78 / 180	10%	0.45	42 / 430
pancreas	2%	31.24	7 / 328	49%	5.25	87 / 178
adrenal gland	9%	249.98	24 / 258	37%	4.46	86 / 230
uterus	24%	807.16	40 / 170	20%	1.60	92 / 459
brain	0%	9.99	11 / 2642	29%	1.59	204 / 705
tonsil	0%	0	0 / 0	24%	0.85	11 / 45
eye	0%	0	0 / 0	20%	0.89	16 / 80
liver	0%	6.48	1 / 226	17%	0.92	71 / 406
kidney	3%	123.66	3 / 89	12%	0.53	110 / 901
spleen	2%	40.74	6 / 241	0%	0	0 / 0
peripheral blood	0%	8.08	4 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0034755	Biological process	iron ion transmembrane transport
GO_0070207	Biological process	protein homotrimerization
GO_0006879	Biological process	intracellular iron ion homeostasis
GO_0006897	Biological process	endocytosis
GO_0034605	Biological process	cellular response to heat
GO_0009986	Cellular component	cell surface
GO_0005886	Cellular component	plasma membrane
GO_0070287	Molecular function	ferritin receptor activity

Gene name	SCARA5
Protein name	Scavenger receptor class A member 5 (Scavenger receptor hlg)
Synonyms	UNQ2938/PRO28700
Description	FUNCTION: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1). .
Accessions	ENST00000518030.1 [Q6ZMJ2-3] ENST00000354914.8 [Q6ZMJ2-1] ENST00000380385.6 [Q6ZMJ2-4] Q6ZMJ2 ENST00000524352.5 [Q6ZMJ2-2]

SCARA5 report