Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 23% ± 2% | |
| astrocyte | 4 studies | 24% ± 7% | |
| glutamatergic neuron | 4 studies | 36% ± 11% | |
| oligodendrocyte precursor cell | 4 studies | 24% ± 4% | |
| GABAergic neuron | 3 studies | 32% ± 6% | |
| oligodendrocyte | 3 studies | 31% ± 15% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 27% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 742.72 | 328 / 328 | 100% | 25.30 | 178 / 178 |
| prostate | 100% | 1348.44 | 245 / 245 | 100% | 28.35 | 502 / 502 |
| stomach | 100% | 991.68 | 359 / 359 | 100% | 19.03 | 286 / 286 |
| breast | 100% | 1106.90 | 459 / 459 | 100% | 31.04 | 1116 / 1118 |
| kidney | 100% | 1335.73 | 89 / 89 | 100% | 33.94 | 899 / 901 |
| lung | 100% | 928.81 | 578 / 578 | 100% | 25.63 | 1152 / 1155 |
| thymus | 100% | 1434.95 | 653 / 653 | 100% | 32.49 | 603 / 605 |
| brain | 100% | 891.69 | 2637 / 2642 | 100% | 28.52 | 704 / 705 |
| uterus | 100% | 1196.57 | 170 / 170 | 100% | 25.79 | 457 / 459 |
| esophagus | 100% | 1015.26 | 1444 / 1445 | 99% | 18.06 | 182 / 183 |
| intestine | 100% | 1155.32 | 966 / 966 | 99% | 20.69 | 523 / 527 |
| skin | 100% | 1242.56 | 1809 / 1809 | 99% | 28.10 | 468 / 472 |
| ovary | 100% | 1185.32 | 180 / 180 | 99% | 18.79 | 426 / 430 |
| liver | 100% | 777.09 | 226 / 226 | 99% | 19.26 | 402 / 406 |
| bladder | 100% | 1258.71 | 21 / 21 | 99% | 26.04 | 499 / 504 |
| adrenal gland | 100% | 1254.75 | 258 / 258 | 96% | 19.02 | 220 / 230 |
| adipose | 100% | 938.86 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1381.76 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 27.04 | 29 / 29 |
| muscle | 100% | 1079.71 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 941.66 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 24.11 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.03 | 1 / 1 |
| heart | 99% | 809.21 | 851 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 22.12 | 79 / 80 |
| peripheral blood | 87% | 716.82 | 810 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0036503 | Biological process | ERAD pathway |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0061630 | Molecular function | ubiquitin protein ligase activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | RNF121 |
| Protein name | Ring finger protein 121 RNF121 protein E3 ubiquitin ligase RNF121 (EC 2.3.2.27) (RING finger protein 121) |
| Synonyms | hCG_1811369 |
| Description | FUNCTION: E3 ubiquitin ligase which accepts ubiquitin and transfers it to substrates thereby promoting their degradation by the endoplasmic reticulum-associated degradation (ERAD) pathway which is a pathway involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (By similarity). May regulate the unfolded protein response to reduce endoplasmic reticulum stress (By similarity). . |
| Accessions | C9JQY5 ENST00000525243.5 ENST00000533380.5 Q9H920 G3V148 ENST00000530137.1 H0YEH6 ENST00000361756.8 [Q9H920-1] E9PRV6 E9PLR7 F8WDV7 ENST00000530058.5 ENST00000530655.5 E9PN80 ENST00000393711.7 ENST00000526549.5 ENST00000393713.7 A0PJP0 E9PKE9 |
