I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| adipocyte | 9 studies | 41% ± 10% | |
| enterocyte | 6 studies | 23% ± 7% | |
| epithelial cell | 5 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| adipocyte | 9 studies | 41% ± 10% | |
| enterocyte | 6 studies | 23% ± 7% | |
| epithelial cell | 5 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 5263.50 | 1808 / 1809 | 100% | 109.90 | 472 / 472 |
| breast | 100% | 12204.36 | 459 / 459 | 100% | 92.20 | 1113 / 1118 |
| liver | 100% | 6281.96 | 226 / 226 | 100% | 101.30 | 404 / 406 |
| stomach | 99% | 4117.46 | 357 / 359 | 100% | 68.38 | 286 / 286 |
| kidney | 100% | 3254.07 | 89 / 89 | 99% | 78.28 | 894 / 901 |
| prostate | 100% | 2942.15 | 244 / 245 | 100% | 82.78 | 500 / 502 |
| esophagus | 100% | 3982.00 | 1441 / 1445 | 99% | 52.27 | 182 / 183 |
| thymus | 100% | 6936.21 | 653 / 653 | 99% | 82.79 | 599 / 605 |
| intestine | 99% | 7393.58 | 961 / 966 | 99% | 79.10 | 523 / 527 |
| bladder | 100% | 3151.62 | 21 / 21 | 98% | 57.90 | 493 / 504 |
| pancreas | 98% | 3168.08 | 321 / 328 | 99% | 76.55 | 176 / 178 |
| lung | 97% | 2986.34 | 561 / 578 | 99% | 52.29 | 1145 / 1155 |
| brain | 96% | 2535.33 | 2546 / 2642 | 100% | 59.74 | 702 / 705 |
| uterus | 99% | 2480.56 | 169 / 170 | 96% | 43.47 | 442 / 459 |
| adrenal gland | 100% | 9268.75 | 258 / 258 | 90% | 36.51 | 206 / 230 |
| ovary | 99% | 2250.92 | 178 / 180 | 81% | 21.24 | 348 / 430 |
| adipose | 100% | 16258.06 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 72.48 | 80 / 80 |
| spleen | 100% | 2115.02 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 35.42 | 1 / 1 |
| muscle | 100% | 6806.02 | 800 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 3005.51 | 1320 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 51.11 | 44 / 45 |
| heart | 85% | 2162.88 | 733 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 20.43 | 21 / 29 |
| peripheral blood | 39% | 715.20 | 361 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042572 | Biological process | retinol metabolic process |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0005640 | Cellular component | nuclear outer membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0051786 | Molecular function | all-trans-retinol 13,14-reductase activity |
| Gene name | RETSAT |
| Protein name | All-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat) (PPAR-alpha-regulated and starvation-induced gene protein) All-trans-retinol 13,14-reductase (EC 1.3.99.23) Retinol saturase |
| Synonyms | PPSIG UNQ439/PRO872 |
| Description | FUNCTION: Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation. . |
| Accessions | ENST00000709863.1 [Q6NUM9-1] H7C3J0 ENST00000295802.9 [Q6NUM9-1] H7BZ16 ENST00000438611.4 H0YGU3 Q6NUM9 ENST00000409984.2 H7BZ81 ENST00000429806.5 ENST00000449375.1 I0EZ74 |
