RDH5 | OmnibusX

Name	Number of supported studies	Average coverage
retinal pigment epithelial cell	4 studies	57% ± 16%	Explore
adipocyte	3 studies	47% ± 13%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of RDH5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	674.13	89 / 89	83%	4.30	748 / 901
liver	99%	1976.58	224 / 226	76%	3.27	310 / 406
ovary	97%	418.64	175 / 180	69%	2.47	298 / 430
thymus	97%	493.40	634 / 653	68%	3.23	414 / 605
intestine	100%	1228.28	966 / 966	55%	1.07	290 / 527
stomach	89%	497.62	321 / 359	55%	1.15	158 / 286
skin	93%	461.73	1676 / 1809	40%	1.59	187 / 472
esophagus	95%	730.69	1367 / 1445	37%	0.68	67 / 183
bladder	95%	635.38	20 / 21	23%	0.44	117 / 504
uterus	98%	492.86	166 / 170	20%	0.54	91 / 459
breast	100%	2568.98	457 / 459	18%	0.38	200 / 1118
brain	63%	192.72	1653 / 2642	52%	1.42	364 / 705
prostate	98%	661.96	240 / 245	14%	0.20	69 / 502
lung	85%	303.79	490 / 578	19%	0.35	219 / 1155
ureter	0%	0	0 / 0	100%	1.16	1 / 1
adipose	100%	3655.83	1203 / 1204	0%	0	0 / 0
blood vessel	100%	1111.49	1333 / 1335	0%	0	0 / 0
spleen	100%	593.82	240 / 241	0%	0	0 / 0
heart	96%	889.66	827 / 861	0%	0	0 / 0
muscle	88%	447.79	707 / 803	0%	0	0 / 0
pancreas	26%	64.44	85 / 328	54%	1.09	96 / 178
adrenal gland	71%	233.92	183 / 258	4%	0.07	9 / 230
peripheral blood	60%	224.28	558 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	21%	0.27	6 / 29
tonsil	0%	0	0 / 0	9%	0.19	4 / 45
eye	0%	0	0 / 0	5%	0.54	4 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007601	Biological process	visual perception
GO_0001523	Biological process	retinoid metabolic process
GO_0008202	Biological process	steroid metabolic process
GO_0042572	Biological process	retinol metabolic process
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0044297	Cellular component	cell body
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0042803	Molecular function	protein homodimerization activity
GO_0004745	Molecular function	all-trans-retinol dehydrogenase (NAD+) activity
GO_0047044	Molecular function	androstan-3-alpha,17-beta-diol dehydrogenase activity
GO_0106429	Molecular function	11-cis-retinol dehydrogenase
GO_0047023	Molecular function	androsterone dehydrogenase activity

Gene name	RDH5
Protein name	Retinol dehydrogenase 5 Retinol dehydrogenase 5 (EC 1.1.1.209) (EC 1.1.1.315) (EC 1.1.1.53) (11-cis retinol dehydrogenase) (11-cis RDH) (11-cis RoDH) (9-cis retinol dehydrogenase) (9cRDH) (Short chain dehydrogenase/reductase family 9C member 5)
Synonyms	RDH1 HSD17B9 SDR9C5
Description	FUNCTION: Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner . Has no activity towards all-trans retinal (By similarity). Plays a significant role in 11-cis retinol oxidation in the retinal pigment epithelium cells (RPE). Also recognizes steroids (androsterone, androstanediol) as its substrates . .
Accessions	ENST00000547072.5 F8VVC7 H0YHP7 ENST00000257895.10 F8VUB9 ENST00000552930.5 ENST00000548082.1 ENST00000548123.1 Q92781

RDH5 report