RAD21L1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of RAD21L1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RAD21L1 at tissue level.

III. Associated gene sets

GO_0051321Biological processmeiotic cell cycle
GO_0007062Biological processsister chromatid cohesion
GO_1990414Biological processreplication-born double-strand break repair via sister chromatid exchange
GO_0007059Biological processchromosome segregation
GO_0030893Cellular componentmeiotic cohesin complex
GO_0005694Cellular componentchromosome
GO_0005634Cellular componentnucleus
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene nameRAD21L1
Protein nameDouble-strand-break repair protein rad21-like protein 1
RAD21 cohesin complex component like 1
SynonymsRAD21L
DescriptionFUNCTION: Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis. Probably required during early meiosis in males for separation of sister chromatids and homologous chromosomes. Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I. Involved in synaptonemal complex assembly, synapsis initiation and crossover recombination between homologous chromosomes during prophase I (By similarity). .

AccessionsENST00000683101.1
ENST00000402452.5 [Q9H4I0-2]
A0A140T8W2
Q9H4I0
A0A804HJ87
ENST00000246108.3
ENST00000409241.5 [Q9H4I0-1]