QSOX2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of QSOX2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of QSOX2 at tissue level.

III. Associated gene sets

GO_0006457Biological processprotein folding
GO_0005615Cellular componentextracellular space
GO_0000139Cellular componentGolgi membrane
GO_0005654Cellular componentnucleoplasm
GO_0005794Cellular componentGolgi apparatus
GO_0031965Cellular componentnuclear membrane
GO_0005886Cellular componentplasma membrane
GO_0003756Molecular functionprotein disulfide isomerase activity
GO_0016971Molecular functionflavin-dependent sulfhydryl oxidase activity

IV. Literature review

[source]
Gene nameQSOX2
Protein nameSulfhydryl oxidase 2 (EC 1.8.3.2) (Neuroblastoma-derived sulfhydryl oxidase) (Quiescin Q6-like protein 1)
Sulfhydryl oxidase (EC 1.8.3.2)
SynonymsQSCN6L1
SOXN
DescriptionFUNCTION: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. .

AccessionsH0Y430
ENST00000455222.1
ENST00000358701.10
Q6ZRP7