PTGR3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045599Biological processnegative regulation of fat cell differentiation
GO_0008150Biological processbiological_process
GO_0006693Biological processprostaglandin metabolic process
GO_0005777Cellular componentperoxisome
GO_0036132Molecular function13-prostaglandin reductase activity
GO_0008270Molecular functionzinc ion binding
GO_0003674Molecular functionmolecular_function
GO_0047522Molecular function15-oxoprostaglandin 13-oxidase activity

IV. Literature review

[source]
Gene namePTGR3
Protein nameZADH2 protein
Prostaglandin reductase 3 (PRG-3) (EC 1.3.1.48) (Zinc-binding alcohol dehydrogenase domain-containing protein 2)
Prostaglandin reductase 3
SynonymsZADH2
DescriptionFUNCTION: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. .

AccessionsENST00000537114.2 [Q8N4Q0-2]
Q4G1C4
ENST00000322342.4 [Q8N4Q0-1]
Q8N4Q0
J3QQQ7
ENST00000581620.1
J3KTQ8
ENST00000582437.1