PTCH2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
glutamatergic neuron	4 studies	40% ± 22%	Explore
GABAergic neuron	3 studies	42% ± 17%	Explore
astrocyte	3 studies	24% ± 12%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	3 studies	33% ± 16%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	92%	1255.64	2440 / 2642	100%	7.63	702 / 705
prostate	99%	725.05	242 / 245	83%	1.74	415 / 502
ovary	100%	5305.66	180 / 180	69%	2.67	297 / 430
thymus	97%	1128.46	633 / 653	58%	1.30	349 / 605
adrenal gland	96%	656.41	247 / 258	57%	1.28	130 / 230
breast	83%	826.54	379 / 459	67%	1.96	746 / 1118
uterus	99%	1547.86	168 / 170	42%	1.43	195 / 459
intestine	83%	571.13	799 / 966	51%	1.45	271 / 527
bladder	95%	701.48	20 / 21	34%	0.67	173 / 504
esophagus	68%	500.88	978 / 1445	51%	1.75	93 / 183
stomach	45%	320.81	163 / 359	58%	2.57	165 / 286
skin	62%	492.74	1124 / 1809	37%	1.83	175 / 472
spleen	97%	530.93	234 / 241	0%	0	0 / 0
pancreas	8%	26.59	25 / 328	87%	3.34	155 / 178
blood vessel	90%	512.96	1205 / 1335	0%	0	0 / 0
kidney	38%	173.07	34 / 89	50%	1.11	453 / 901
lung	35%	128.79	205 / 578	42%	2.30	490 / 1155
adipose	68%	640.92	817 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	1.65	18 / 29
muscle	47%	176.24	376 / 803	0%	0	0 / 0
liver	11%	33.88	24 / 226	13%	0.45	54 / 406
heart	23%	88.58	200 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	18%	0.37	8 / 45
eye	0%	0	0 / 0	15%	0.19	12 / 80
peripheral blood	0%	0.34	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1