PRRT1 | OmnibusX

Name	Number of supported studies	Average coverage
retinal bipolar neuron	3 studies	26% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRRT1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	5574.16	2634 / 2642	100%	26.26	703 / 705
ovary	100%	3501.82	180 / 180	71%	4.86	307 / 430
prostate	95%	905.32	232 / 245	66%	2.26	331 / 502
adrenal gland	74%	457.77	190 / 258	81%	20.62	186 / 230
uterus	95%	853.97	162 / 170	57%	2.92	260 / 459
bladder	95%	673.57	20 / 21	45%	2.27	226 / 504
breast	68%	441.92	310 / 459	60%	2.78	666 / 1118
skin	45%	233.54	816 / 1809	82%	5.19	387 / 472
esophagus	76%	633.50	1097 / 1445	42%	1.78	76 / 183
thymus	75%	463.23	493 / 653	33%	1.52	201 / 605
intestine	88%	776.82	851 / 966	18%	0.75	97 / 527
kidney	60%	413.22	53 / 89	41%	1.54	372 / 901
ureter	0%	0	0 / 0	100%	3.69	1 / 1
blood vessel	95%	816.90	1263 / 1335	0%	0	0 / 0
stomach	54%	396.22	193 / 359	30%	1.30	87 / 286
eye	0%	0	0 / 0	70%	3.17	56 / 80
lung	43%	238.66	246 / 578	23%	1.04	266 / 1155
pancreas	1%	3.15	2 / 328	51%	2.21	90 / 178
adipose	46%	235.97	548 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	20%	0.55	9 / 45
heart	20%	103.98	168 / 861	0%	0	0 / 0
spleen	18%	90.87	44 / 241	0%	0	0 / 0
liver	2%	8.25	4 / 226	5%	0.20	21 / 406
peripheral blood	0%	0.82	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006468	Biological process	protein phosphorylation
GO_0050808	Biological process	synapse organization
GO_0060292	Biological process	long-term synaptic depression
GO_0060291	Biological process	long-term synaptic potentiation
GO_0034394	Biological process	protein localization to cell surface
GO_2000311	Biological process	regulation of AMPA receptor activity
GO_0007611	Biological process	learning or memory
GO_0098839	Cellular component	postsynaptic density membrane
GO_0030672	Cellular component	synaptic vesicle membrane
GO_0016020	Cellular component	membrane
GO_0030545	Molecular function	signaling receptor regulator activity

Gene name	PRRT1
Protein name	Proline rich transmembrane protein 1 Proline-rich transmembrane protein 1 Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1) (Synapse differentiation-induced protein 4) (SynDIG4)
Synonyms	C6orf31 NG5
Description	FUNCTION: Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression. .
Accessions	ENST00000441129.5 [Q99946-2] ENST00000419655.6 [Q99946-1] ENST00000437574.5 ENST00000456814.6 [Q99946-1] ENST00000425739.5 [Q99946-2] ENST00000444466.6 [Q99946-1] ENST00000451329.6 [Q99946-1] ENST00000445122.5 [Q99946-2] ENST00000444218.5 ENST00000458719.6 [Q99946-1] ENST00000383309.6 [Q99946-2] ENST00000423003.5 ENST00000414687.6 [Q99946-1] A0A0G2JI65 ENST00000457819.5 ENST00000439937.5 ENST00000418753.5 [Q99946-2] ENST00000423671.5 [Q99946-2] ENST00000454112.6 [Q99946-1] ENST00000452030.5 [Q99946-2] Q99946 A0A8Z5AAT7 ENST00000425067.5 ENST00000375150.6 ENST00000419839.5 ENST00000211413.10 [Q99946-1]

PRRT1 report