PRPS1L1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PRPS1L1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRPS1L1 at tissue level.

III. Associated gene sets

GO_0008584Biological processmale gonad development
GO_0006015Biological process5-phosphoribose 1-diphosphate biosynthetic process
GO_0006164Biological processpurine nucleotide biosynthetic process
GO_0009156Biological processribonucleoside monophosphate biosynthetic process
GO_0005575Cellular componentcellular_component
GO_0002189Cellular componentribose phosphate diphosphokinase complex
GO_0005737Cellular componentcytoplasm
GO_0042803Molecular functionprotein homodimerization activity
GO_0004749Molecular functionribose phosphate diphosphokinase activity
GO_0005524Molecular functionATP binding
GO_0000287Molecular functionmagnesium ion binding
GO_0016301Molecular functionkinase activity

IV. Literature review

[source]
Gene namePRPS1L1
Protein nameribose-phosphate diphosphokinase (EC 2.7.6.1)
Ribose-phosphate pyrophosphokinase 3 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 1-like 1) (PRPS1-like 1) (Phosphoribosyl pyrophosphate synthase III) (PRS-III)
SynonymsPRPSL
PRPS3
DescriptionFUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

FUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. .

AccessionsA0A0B4J207
ENST00000506618.5
ENST00000506618
P21108