Insufficient scRNA-seq data for expression of PRODH at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 97% | 2039.90 | 2560 / 2642 | 83% | 4.73 | 583 / 705 |
| lung | 76% | 1659.80 | 439 / 578 | 78% | 8.84 | 900 / 1155 |
| kidney | 74% | 750.16 | 66 / 89 | 74% | 5.94 | 670 / 901 |
| thymus | 75% | 625.71 | 489 / 653 | 66% | 2.11 | 398 / 605 |
| esophagus | 63% | 438.77 | 905 / 1445 | 63% | 3.06 | 115 / 183 |
| breast | 63% | 627.51 | 287 / 459 | 48% | 2.99 | 534 / 1118 |
| skin | 72% | 1939.28 | 1304 / 1809 | 24% | 0.91 | 112 / 472 |
| liver | 47% | 532.24 | 106 / 226 | 44% | 4.48 | 180 / 406 |
| muscle | 87% | 1868.97 | 699 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 7.27 | 38 / 45 |
| uterus | 15% | 75.49 | 26 / 170 | 62% | 3.20 | 286 / 459 |
| intestine | 39% | 527.19 | 378 / 966 | 35% | 1.41 | 183 / 527 |
| bladder | 33% | 244.52 | 7 / 21 | 34% | 1.94 | 170 / 504 |
| stomach | 26% | 154.70 | 93 / 359 | 33% | 1.61 | 95 / 286 |
| eye | 0% | 0 | 0 / 0 | 56% | 1.84 | 45 / 80 |
| heart | 47% | 406.05 | 403 / 861 | 0% | 0 | 0 / 0 |
| adipose | 45% | 442.01 | 544 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 40% | 344.55 | 539 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 34% | 202.37 | 84 / 245 | 3% | 0.04 | 14 / 502 |
| pancreas | 2% | 7.91 | 6 / 328 | 26% | 0.97 | 46 / 178 |
| ovary | 3% | 9.91 | 5 / 180 | 11% | 0.30 | 46 / 430 |
| adrenal gland | 2% | 23.93 | 6 / 258 | 3% | 0.04 | 6 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.05 | 1 / 29 |
| spleen | 0% | 2.53 | 1 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 1.24 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0010133 | Biological process | proline catabolic process to glutamate |
| GO_0019470 | Biological process | 4-hydroxyproline catabolic process |
| GO_0008631 | Biological process | intrinsic apoptotic signaling pathway in response to oxidative stress |
| GO_1903376 | Biological process | regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway |
| GO_0006560 | Biological process | proline metabolic process |
| GO_0006562 | Biological process | proline catabolic process |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0071949 | Molecular function | FAD binding |
| GO_0004657 | Molecular function | proline dehydrogenase activity |
| Gene name | PRODH |
| Protein name | Proline dehydrogenase (EC 1.5.5.2) Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Proline oxidase 2) (p53-induced gene 6 protein) Proline dehydrogenase 1 |
| Synonyms | PIG6 PRODH2 POX2 |
| Description | FUNCTION: Converts proline to delta-1-pyrroline-5-carboxylate. . FUNCTION: Converts proline to delta-1-pyrroline-5-carboxylate. . FUNCTION: Converts proline to delta-1-pyrroline-5-carboxylate. . FUNCTION: Converts proline to delta-1-pyrroline-5-carboxylate. . FUNCTION: Converts proline to delta-1-pyrroline-5-carboxylate. . FUNCTION: Converts proline to delta-1-pyrroline-5-carboxylate. . FUNCTION: Converts proline to delta-1-pyrroline-5-carboxylate. . |
| Accessions | A0A481ZHW6 C9JIW4 ENST00000450579.1 H7C3U9 X5D7N2 ENST00000334029.6 ENST00000438924.5 ENST00000457083.1 ENST00000357068.11 E7EQL6 H7C363 ENST00000610940.4 A0A481ZII7 ENST00000420436.5 O43272 A0A087WWM6 |
